Thomas E Wooters
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Explore the profile of Thomas E Wooters including associated specialties, affiliations and a list of published articles.
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13
Citations
232
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Recent Articles
1.
Beckmann J, Meyer A, Pivavarchyk M, Horton D, Zheng G, Smith A, et al.
Neurochem Res
. 2015 Aug;
40(10):2121-30.
PMID: 26227997
α6β2* nicotinic acetylcholine receptors (nAChRs) expressed by dopaminergic neurons mediate nicotine-evoked dopamine (DA) release and nicotine reinforcement. α6β2* antagonists inhibit these effects of nicotine, such that α6β2* receptors serve as...
2.
Wooters T, Dwoskin L, Bardo M
Behav Pharmacol
. 2011 Aug;
22(5-6):516-24.
PMID: 21836462
Glutamate contributes to the reinforcing and stimulant effects of methamphetamine, yet its potential role in the interoceptive stimulus properties of methamphetamine is unknown. In this study, adult male Sprague-Dawley rats...
3.
Wooters T, Bardo M
Brain Res
. 2011 May;
1396:45-53.
PMID: 21570676
Impulsivity is one of the core symptoms of attention-deficit/hyperactivity disorder (ADHD). The spontaneously hypertensive rat (SHR), a putative animal model of ADHD, has been used to investigate the neurobiology of...
4.
Wooters T, Smith A, Pivavarchyk M, Siripurapu K, McIntosh J, Zhang Z, et al.
Br J Pharmacol
. 2011 Jan;
163(2):346-57.
PMID: 21232049
Background And Purpose: Nicotinic acetylcholine receptors (nAChRs) containing α6β2 subunits expressed by dopamine neurons regulate nicotine-evoked dopamine release. Previous results show that the α6β2* nAChR antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) inhibits...
5.
Wooters T, Bardo M, Dwoskin L, Midde N, Gomez A, Mactutus C, et al.
Behav Brain Res
. 2011 Jan;
219(1):98-107.
PMID: 21219939
Rats raised in an enriched condition (EC) are less sensitive to the locomotor effects of stimulant drugs than rats raised in an impoverished condition (IC). Methylphenidate (MPD), a primary pharmacotherapy...
6.
Wooters T, Walton M, Bardo M
Neurosci Lett
. 2010 Oct;
487(3):293-6.
PMID: 20974224
Emerging data suggest that illicit methylphenidate abuse is a growing problem. Although abuse of the drug typically occurs by the intranasal route, oral (per os; p.o.) methylphenidate also has abuse...
7.
Wooters T, Bevins R, Bardo M
Curr Drug Abuse Rev
. 2010 May;
2(3):243-55.
PMID: 20443771
Preclinical drug discrimination techniques play a significant role in advancing our knowledge of the receptor mechanisms underlying the interoceptive effects of nicotine. Early reports confirmed that nicotinic acetylcholine receptors (nAChRs)...
8.
Smith A, Pivavarchyk M, Wooters T, Zhang Z, Zheng G, McIntosh J, et al.
Biochem Pharmacol
. 2010 Mar;
80(3):402-9.
PMID: 20346923
The novel nicotinic receptor (nAChR) antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), and its chemically reduced analog, r-bPiDDB, potently inhibit nicotine-evoked dopamine (DA) release from rat striatal slices. Since tobacco smokers self-administer nicotine...
9.
Dwoskin L, Smith A, Wooters T, Zhang Z, Crooks P, Bardo M
Biochem Pharmacol
. 2009 Jun;
78(7):732-43.
PMID: 19523455
Tobacco dependence is the most preventable cause of death and is a chronic, relapsing disorder in which compulsive tobacco use persists despite known negative health consequences. All currently available cessation...
10.
Wooters T, Bardo M
Psychopharmacology (Berl)
. 2009 Feb;
204(3):551-62.
PMID: 19229521
Rationale: Nicotinic acetylcholine receptors (nAChRs) regulate sensitization to stimulant drugs such as d-amphetamine and cocaine. Objectives: The current study determined if nAChRs modulate the induction and/or expression of behavioral sensitization...