Michael T Bardo
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Explore the profile of Michael T Bardo including associated specialties, affiliations and a list of published articles.
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138
Citations
2707
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Recent Articles
1.
Malone S, Tavakoli N, Keller P, Bardo M, Ortinski P
Neuropharmacology
. 2025 Feb;
271:110370.
PMID: 39988277
The central amygdala (CeA) is involved in opioid relapse-associated behaviors. This study determined if escalation of fentanyl intake as modeled by long-access (LgA) self-administration (SA) alters ex vivo neuronal activity...
2.
Keady J, Charnigo R, Shaykin J, Prantzalos E, Prantzalos E, Xia M, et al.
bioRxiv
. 2024 Dec;
PMID: 39713469
Background: The "loss of control" over drug consumption, present in opioid use disorder (OUD) and known as escalation of intake, is well-established in preclinical rodent models. However, little is known...
3.
Tavakoli N, Malone S, Anderson T, Neeley R, Asadipooya A, Bardo M, et al.
Front Cell Neurosci
. 2024 Sep;
18:1347491.
PMID: 39280793
Recent literature supports a prominent role for astrocytes in regulation of drug-seeking behaviors. The dorsal striatum, specifically, is known to play a role in reward processing with neuronal activity that...
4.
Shaykin J, Olyha L, Van Doorn C, Hales J, Chandler C, Hopkins D, et al.
Drug Alcohol Depend Rep
. 2024 Sep;
12:100277.
PMID: 39262667
Background: Alcohol use in adolescence may increase susceptibility to substance use disorders (SUDs) in adulthood. This study determined if voluntary ethanol (EtOH) consumption during adolescence, combined with social isolation, alters...
5.
Shaykin J, Denehy E, Martin J, Chandler C, Luo D, Taylor C, et al.
Environ Toxicol Pharmacol
. 2024 Aug;
110:104527.
PMID: 39106924
This study assessed the ability of α and α-adrenergic drugs to decrease fentanyl-induced locomotor and ventilatory depression. Rats were given saline or fentanyl, followed by: (1) naltrexone, (2) naloxone, (3)...
6.
Vu L, Luo D, Johnson K, Denehy E, Songrady J, Martin J, et al.
J Med Chem
. 2024 May;
67(11):9173-9193.
PMID: 38810170
While in the process of designing more effective synthetic opioid rescue agents, we serendipitously identified a new chemotype of potent synthetic opioid. Here, we report that conformational constraint of a...
7.
Chandler C, Nickell J, George Wilson A, Culver J, Crooks P, Bardo M, et al.
Biochem Pharmacol
. 2024 Apr;
228:116189.
PMID: 38580165
Previous research has demonstrated therapeutic potential for VMAT2 inhibitors in rat models of methamphetamine use disorder. Here, we report on the neurochemical and behavioral effects of 1-(2-methoxyphenethyl)-4-phenethypiperazine (JPC-141), a novel...
8.
Wooden J, Peacoe L, Anasooya Shaji C, Melbourne J, Chandler C, Bardo M, et al.
Cells
. 2023 Nov;
12(21).
PMID: 37947650
During adolescence, the brain is highly susceptible to alcohol-induced damage and subsequent neuroimmune responses, effects which may enhance development of an alcohol use disorder (AUD). Neuroimmune reactions are implicated in...
9.
Humburg B, Bardo M
Psychopharmacology (Berl)
. 2023 Jun;
PMID: 37391496
Rationale: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli. Objectives: This...
10.
Radevski M, Prendergast M, Bardo M, Akins C
Psychopharmacology (Berl)
. 2023 Jan;
240(2):295-301.
PMID: 36607385
Rationale: Alcohol use disorder (AUD) has been shown to be associated with a dysregulated stress system. Reducing the stress hormone corticosterone (CORT), that binds to glucocorticoid receptors, may attenuate the...