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Thomas Cantore

Explore the profile of Thomas Cantore including associated specialties, affiliations and a list of published articles. Areas
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Citations 24
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Recent Articles
1.
Cantore T, Gasperini P, Bevilacqua R, Ciani Y, Sinha S, Ruppin E, et al.
Genome Biol . 2025 Feb; 26(1):42. PMID: 40022167
Gene context-essentiality assessment supports precision oncology opportunities. The variability of gene effects inference from loss-of-function screenings across models and technologies limits identifying robust hits. We propose a computational framework named...
2.
Fracassi G, Lorenzin F, Orlando F, Gioia U, DAmato G, Casaramona A, et al.
J Clin Invest . 2024 Dec; 135(4). PMID: 39718835
PARP inhibitors (PARPi) have received regulatory approval for the treatment of several tumors, including prostate cancer (PCa), and demonstrate remarkable results in the treatment of castration-resistant prostate cancer (CRPC) patients...
3.
Minoli M, Cantore T, Hanhart D, Kiener M, Fedrizzi T, La Manna F, et al.
Nat Commun . 2023 Apr; 14(1):2214. PMID: 37072390
Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs) have been successfully used...
4.
Fedrizzi T, Ciani Y, Lorenzin F, Cantore T, Gasperini P, Demichelis F
Comput Struct Biotechnol J . 2021 Aug; 19:4394-4403. PMID: 34429855
Mutual Exclusivity analysis of genomic aberrations contributes to the exploration of potential synthetic lethal (SL) relationships thus guiding the nomination of specific cancer cells vulnerabilities. When multiple classes of genomic...
5.
Ciciani M, Cantore T, Lauria M
Bioinformatics . 2020 May; 36(13):4095-4096. PMID: 32399554
Summary: The classification of biological samples by means of their respective molecular profiles is a topic of great interest for its potential diagnostic, prognostic and investigational applications. rScudo is an...