Thomas B Nicholson
Overview
Explore the profile of Thomas B Nicholson including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
502
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0
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Recent Articles
1.
Li J, Canham S, Wu H, Henault M, Chen L, Liu G, et al.
Nat Chem Biol
. 2023 Oct;
20(3):365-372.
PMID: 37828400
Stimulator of interferon genes (STING) is a dimeric transmembrane adapter protein that plays a key role in the human innate immune response to infection and has been therapeutically exploited for...
2.
Paul A, Annunziato S, Lu B, Sun T, Evrova O, Planas-Paz L, et al.
Nat Commun
. 2022 Feb;
13(1):930.
PMID: 35177623
The Hippo/YAP pathway controls cell proliferation through sensing physical and spatial organization of cells. How cell-cell contact is sensed by Hippo signaling is poorly understood. Here, we identified the cell...
3.
Ghoshal A, Uygun D, Yang L, McNally J, Lopez-Huerta V, Arias-Garcia M, et al.
Transl Psychiatry
. 2020 Feb;
10(1):29.
PMID: 32066662
CACNA1I, a schizophrenia risk gene, encodes a subtype of voltage-gated T-type calcium channel Ca3.3. We previously reported that a patient-derived missense de novo mutation (R1346H) of CACNA1I impaired Ca3.3 channel...
4.
Tang C, Ksiazek I, Siccardi N, Gapp B, Weber D, Wirsching J, et al.
Endocrinology
. 2019 Sep;
160(12):2849-2860.
PMID: 31556942
The gut-pancreas axis plays a key role in the regulation of glucose homeostasis and may be therapeutically exploited to treat not only type 2 diabetes but also hypoglycemia and hyperinsulinemia....
5.
Planas-Paz L, Sun T, Pikiolek M, Cochran N, Bergling S, Orsini V, et al.
Cell Stem Cell
. 2019 May;
25(1):39-53.e10.
PMID: 31080135
Biliary epithelial cells (BECs) form bile ducts in the liver and are facultative liver stem cells that establish a ductular reaction (DR) to support liver regeneration following injury. Liver damage...
6.
Takase R, Hino S, Nagaoka K, Anan K, Kohrogi K, Araki H, et al.
FASEB J
. 2019 Jan;
33(4):5300-5311.
PMID: 30681884
Transcriptional and epigenetic regulation is fundamentally involved in initiating and maintaining progression of cellular differentiation. The 2 types of thermogenic adipocytes, brown and beige, are thought to be of different...
7.
Lynch J, Li B, Katoli P, Xiang C, Leehy B, Rangaswamy N, et al.
J Biol Chem
. 2018 Nov;
293(52):20137-20156.
PMID: 30389787
Myocilin () was discovered more than 20 years ago and is the gene whose mutations are most commonly observed in individuals with glaucoma. Despite extensive research efforts, the function of...
8.
Calabretta S, Vogel G, Yu Z, Choquet K, Darbelli L, Nicholson T, et al.
Dev Cell
. 2018 Jul;
46(4):426-440.e5.
PMID: 30057274
The oligodendrocyte lineage is responsible for myelination of the central nervous system. Post-translational modifications are known to regulate oligodendrocyte precursor cell (OPC) differentiation into mature myelinating oligodendrocytes. The role of...
9.
Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, et al.
Nat Cell Biol
. 2016 Oct;
18(11):1260.
PMID: 27784900
No abstract available.
10.
Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, et al.
Nat Cell Biol
. 2016 Apr;
18(5):467-79.
PMID: 27088858
LGR4/5 receptors and their cognate RSPO ligands potentiate Wnt/β-catenin signalling and promote proliferation and tissue homeostasis in epithelial stem cell compartments. In the liver, metabolic zonation requires a Wnt/β-catenin signalling...