Thomas B Nicholson
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Explore the profile of Thomas B Nicholson including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
502
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Recent Articles
11.
Nicholson T, Singh A, Su H, Hevi S, Wang J, Bajko J, et al.
PLoS One
. 2013 May;
8(4):e60913.
PMID: 23637775
Lysine-specific demethylase 1 (Lsd1/Aof2/Kdm1a), the first enzyme with specific lysine demethylase activity to be described, demethylates histone and non-histone proteins and is essential for mouse embryogenesis. Lsd1 interacts with numerous...
12.
Nicholson T, Su H, Hevi S, Wang J, Bajko J, Li M, et al.
Cell Res
. 2012 Apr;
PMID: 22491473
No abstract available.
13.
Nicholson T, Su H, Hevi S, Wang J, Bajko J, Li M, et al.
Cell Res
. 2011 Dec;
PMID: 22143567
Lysine-specific demethylase 1 (LSD1/AOF2/KDM1A), the first enzyme with specific lysine demethylase activity to be described, demethylates histone and non-histone proteins and is essential for mouse embryogenesis. LSD1 interacts with numerous...
14.
Singh P, Han L, Rivas G, Lee D, Nicholson T, Larson G, et al.
Mol Cell Biol
. 2010 Mar;
30(11):2693-707.
PMID: 20351169
Imprinted gene expression corresponds to parental allele-specific DNA CpG methylation and chromatin composition. Histone tail covalent modifications have been extensively studied, but it is not known whether modifications in the...
15.
Nicholson T, Chen T, Richard S
Pharmacol Res
. 2009 Aug;
60(6):466-74.
PMID: 19643181
Post-translational modifications are well-known effectors in DNA damage signaling and epigenetic gene expression. Protein arginine methylation is a covalent modification that results in the addition of methyl groups to the...
16.
Nicholson T, Chen T
Epigenetics
. 2009 Apr;
4(3):129-32.
PMID: 19395867
One of the key breakthroughs in the epigenetics/chromatin field in the last several years was the identification of enzymes capable of removing the methyl group from methylated lysines in histone...
17.
Nicholson T, Stanners C
J Cell Biol
. 2007 Apr;
177(2):211-8.
PMID: 17438079
Exchanging the glycophosphatidylinositol (GPI) anchor signal sequence of neural cell adhesion molecule (NCAM) for the signal sequence of carcinoembryonic antigen (CEA) generates a mature protein with NCAM external domains but...
18.
Nicholson T, Stanners C
J Cell Biol
. 2006 Nov;
175(4):647-59.
PMID: 17101695
The functional specificity conferred by glycophosphatidylinositol (GPI) anchors on certain membrane proteins may arise from their occupancy of specific membrane microdomains. We show that membrane proteins with noninteractive external domains...