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Thomas A Kohl

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Articles 88
Citations 3442
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Recent Articles
1.
Wetzstein N, Diricks M, Anton T, Andres S, Kuhns M, Kohl T, et al.
Genome Med . 2024 Jul; 16(1):86. PMID: 38982539
Background: The Mycobacterium avium complex (MAC) comprises the most frequent non-tuberculous mycobacteria (NTM) in Central Europe and currently includes twelve species. M. avium (MAV), M. intracellulare subsp. intracellulare (MINT), and...
2.
Dreyer V, Sonnenkalb L, Diricks M, Utpatel C, Barilar I, Mohr V, et al.
Methods Mol Biol . 2024 Jul; 2833:195-210. PMID: 38949712
Whole genome sequencing of Mycobacterium tuberculosis complex (MTBC) isolates has been shown to provide accurate predictions for resistance and susceptibility for many first- and second-line anti-tuberculosis drugs. However, bioinformatic pipelines...
3.
Mohr V, Sonnenkalb L, Utpatel C, Barilar I, Diricks M, Dreyer V, et al.
Methods Mol Biol . 2024 Jul; 2833:185-193. PMID: 38949711
Whole genome sequencing (WGS) is becoming an important diagnostic tool for antimicrobial susceptibility testing of Mycobacterium tuberculosis complex (MTBC) isolates in many countries. WGS protocols usually start with the preparation...
4.
Schlanderer J, Hoffmann H, Luddecke J, Golubov A, Grasse W, Kindler E, et al.
Lab Chip . 2023 Nov; 24(1):74-84. PMID: 37999937
Globally, tuberculosis (TB) remains the deadliest bacterial infectious disease, and spreading antibiotic resistances is the biggest challenge for combatting the disease. Rapid and comprehensive diagnostics including drug susceptibility testing (DST)...
5.
Trauth J, Matt U, Kohl T, Niemann S, Herold S
Eur Heart J Case Rep . 2023 Sep; 7(8):ytad400. PMID: 37654802
Background: The recently published 2023 Duke-ISCVID Criteria for Infective Endocarditis for the first time consider mycobacteria (esp. ) as 'typical' microorganisms for prosthetic valve endocarditis (major criteria). This reflects the...
6.
Tagliani E, Kohl T, Ghodousi A, Groenheit R, Holicka Y, Niemann S, et al.
Clin Microbiol Infect . 2023 Jun; 30(1):4-6. PMID: 37321396
No abstract available.
7.
Perez-Llanos F, Dreyer V, Barilar I, Utpatel C, Kohl T, Murcia M, et al.
Microbiol Spectr . 2023 May; 11(3):e0501322. PMID: 37222610
Whole genome sequencing (WGS) has become the main tool for studying the transmission of Mycobacterium tuberculosis complex (MTBC) strains; however, the clonal expansion of one strain often limits its application...
8.
Wetzstein N, Kohl T, Diricks M, Mas-Peiro S, Holubec T, Kessel J, et al.
Clin Microbiol Infect . 2023 Mar; 29(8):1008-1014. PMID: 36918144
Objectives: Since 2013, heater-cooler unit (HCU) associated Mycobacterium chimaera infections linked to a global outbreak have been described. These infections were characterised by high morbidity and mortality due to delayed...
9.
Merker M, Rasigade J, Barbier M, Cox H, Feuerriegel S, Kohl T, et al.
Nat Commun . 2022 Aug; 13(1):5105. PMID: 36042200
Transmission-driven multi-/extensively drug resistant (M/XDR) tuberculosis (TB) is the largest single contributor to human mortality due to antimicrobial resistance. A few major clades of the Mycobacterium tuberculosis complex belonging to...
10.
Diricks M, Merker M, Wetzstein N, Kohl T, Niemann S, Maurer F
Nat Commun . 2022 Aug; 13(1):4936. PMID: 35999208
Mycobacterium abscessus is an emerging multidrug-resistant non-tuberculous mycobacterium that causes a wide spectrum of infections and has caused several local outbreaks worldwide. To facilitate standardized prospective molecular surveillance, we established...