Thibault Peineau
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Explore the profile of Thibault Peineau including associated specialties, affiliations and a list of published articles.
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6
Citations
39
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Recent Articles
1.
Peineau T, Marcovich I, Rodriguez C, OMalley S, Cui R, Ballesteros A, et al.
Hear Res
. 2025 Mar;
460:109229.
PMID: 40073458
Sensory transduction in auditory hair cells gates mechanosensitive ion channels, converting sound information into electrical signals (Zheng and Holt, 2021). Previously, we found that Transmembrane channel (TMC) proteins 1 and...
2.
Mendia C, Peineau T, Zamani M, Felgerolle C, Yahiaoui N, Christophersen N, et al.
Mol Ther
. 2024 Jan;
32(3):800-817.
PMID: 38243601
Hearing loss is a major health concern affecting millions of people worldwide with currently limited treatment options. In clarin-2-deficient Clrn2 mice, used here as a model of progressive hearing loss,...
3.
Ferraguto C, Bouleau Y, Peineau T, Dulon D, Pietropaolo S
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511622
Hyperacusis, i.e., an increased sensitivity to sounds, is described in several neurodevelopmental disorders (NDDs), including Fragile X Syndrome (FXS). The mechanisms underlying hyperacusis in FXS are still largely unknown and...
4.
Mauriac S, Peineau T, Zuberi A, Lutz C, Geleoc G
Cells
. 2022 Dec;
11(24).
PMID: 36552747
Peroxisome Biogenesis Disorders (PBD) and Zellweger syndrome spectrum disorders (ZSD) are rare genetic multisystem disorders that include hearing impairment and are associated with defects in peroxisome assembly, function, or both....
5.
Calvet C, Peineau T, Benamer N, Cornille M, Lelli A, Plion B, et al.
iScience
. 2022 Dec;
25(12):105628.
PMID: 36483015
Hearing depends on fast and sustained calcium-dependent synaptic vesicle fusion at the ribbon synapses of cochlear inner hair cells (IHCs). The implication of the canonical neuronal SNARE complex in this...
6.
Peineau T, Belleudy S, Pietropaolo S, Bouleau Y, Dulon D
Front Aging Neurosci
. 2021 Nov;
13:756449.
PMID: 34733152
Age-related hidden hearing loss is often described as a cochlear synaptopathy that results from a progressive degeneration of the inner hair cell (IHC) ribbon synapses. The functional changes occurring at...
7.
Dunbar L, Patni P, Aguilar C, Mburu P, Corns L, Wells H, et al.
EMBO Mol Med
. 2019 Aug;
11(9):e10288.
PMID: 31448880
Hearing relies on mechanically gated ion channels present in the actin-rich stereocilia bundles at the apical surface of cochlear hair cells. Our knowledge of the mechanisms underlying the formation and...