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Theodore A Craig

Explore the profile of Theodore A Craig including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 636
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Recent Articles
1.
Kritmetapak K, Singh R, Craig T, Hines J, Kumar R
Biochem Biophys Res Commun . 2021 Jul; 572:15-19. PMID: 34332324
Background: Novel human parathyroid hormone (hPTH) peptides of unknown biological activity have recently been identified in the serum of subjects with normal renal function, chronic renal failure, and end-stage renal...
2.
Du Truong C, Craig T, Cui G, Botuyan M, Serkasevich R, Chan K, et al.
J Biol Chem . 2021 Jun; 297(2):100912. PMID: 34174285
The translesion synthesis (TLS) DNA polymerases Rev1 and Polζ function together in DNA lesion bypass during DNA replication, acting as nucleotide inserter and extender polymerases, respectively. While the structural characterization...
3.
Fogarty M, Losbanos L, Craig T, Reynolds C, Brown A, Kumar R, et al.
J Appl Physiol (1985) . 2021 May; 131(1):95-106. PMID: 34013750
Diseases or conditions where diaphragm muscle (DIAm) function is impaired, including chronic obstructive pulmonary disease, cachexia, asthma, and aging, are associated with an increased risk of pulmonary symptoms, longer duration...
4.
Berent T, Dorschner J, Meyer T, Craig T, Wang X, Kunz H, et al.
PLoS One . 2019 Dec; 14(12):e0226440. PMID: 31851697
Background: To understand the underlying mechanisms of cardiac dysfunction in cancer, we examined cardiac function, protein synthesis, mitochondrial function and gene expression in a model of heart failure in mice...
5.
Berent T, Dorschner J, Craig T, Drake M, Westendorf J, Kumar R
Biochem Biophys Res Commun . 2019 Sep; 519(3):566-571. PMID: 31537378
Patients with non-small cell lung cancer (NSLC) often develop skeletal complications and fractures. To understand mechanisms of bone loss, we developed a murine model of non-metastatic NSLC. Decreased bone mineral...
6.
Ryan Z, Craig T, Wang X, Delmotte P, Salisbury J, Lanza I, et al.
Biochem Biophys Res Commun . 2018 Jan; 496(2):746-752. PMID: 29366785
Cancer cachexia is associated with muscle weakness and atrophy. We investigated whether 1α,25-dihydroxyvitamin D (1α,25(OH)D), which has previously been shown to increase skeletal myoblast oxygen consumption rate, could reverse the...
7.
Zhang J, Li J, Craig T, Kumar R, Gross M
Biochemistry . 2017 Jun; 56(28):3523-3530. PMID: 28627884
Downstream regulatory element antagonist modulator (DREAM) is an EF-hand Ca-binding protein that also binds to a specific DNA sequence, downstream regulatory elements (DRE), and thereby regulates transcription in a calcium-dependent...
8.
Ryan Z, Craig T, Folmes C, Wang X, Lanza I, Schaible N, et al.
J Biol Chem . 2015 Nov; 291(3):1514-28. PMID: 26601949
Muscle weakness and myopathy are observed in vitamin D deficiency and chronic renal failure, where concentrations of the active vitamin D3 metabolite, 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), are low. To evaluate the...
9.
Ryan Z, Craig T, Filoteo A, Westendorf J, Cartwright E, Neyses L, et al.
Biochem Biophys Res Commun . 2015 Sep; 467(1):152-6. PMID: 26392310
The physiological importance of the intestinal plasma membrane calcium pump, isoform 1, (Pmca1, Atp2b1), in calcium absorption and homeostasis has not been previously demonstrated in vivo. Since global germ-line deletion...
10.
Ryan Z, Craig T, McGee-Lawrence M, Westendorf J, Kumar R
J Steroid Biochem Mol Biol . 2014 Dec; 148:225-31. PMID: 25446885
Humans with mutations of the sclerostin (SOST) gene, and knockout animals in which the Sost gene has been experimentally deleted, exhibit an increase in bone mass. We review the mechanisms...