Theodore A Craig
Overview
Explore the profile of Theodore A Craig including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
636
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Recent Articles
11.
Ryan Z, Craig T, Salisbury J, Carpio L, McGee-Lawrence M, Westendorf J, et al.
Biochem Biophys Res Commun
. 2014 May;
448(1):83-8.
PMID: 24780398
We show that prostacyclin production is increased in bone and osteocytes from sclerostin (Sost) knockout mice which have greatly increased bone mass. The addition of prostacyclin or a prostacyclin analog...
12.
Craig T, Zhang Y, Magis A, Funk C, Price N, Ekker S, et al.
Zebrafish
. 2014 Mar;
11(3):207-18.
PMID: 24650217
The sterol hormone, 1α,25-dihydroxyvitamin D₃ (1α,25(OH)₂D₃), regulates gene expression and messenger RNA (mRNA) concentrations in zebrafish in vivo. Since mRNA concentrations and translation are influenced by micro-RNAs (miRNAs), we examined...
13.
Ryan Z, Ketha H, McNulty M, McGee-Lawrence M, Craig T, Grande J, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(15):6199-204.
PMID: 23530237
Inactivating mutations of the SOST (sclerostin) gene are associated with overgrowth and sclerosis of the skeleton. To determine mechanisms by which increased amounts of calcium and phosphorus are accreted to...
14.
Craig T, Ramachandran P, Bergen 3rd H, Podratz J, Windebank A, Kumar R
Biochem Biophys Res Commun
. 2013 Mar;
433(4):508-12.
PMID: 23524266
The EF-hand protein, DREAM/KChIP3 (henceforth referred to as DREAM), regulates apoptosis by incompletely understood mechanisms. We demonstrate that in the presence of Ca2+, DREAM interacts with hexokinase I, a protein...
15.
Ramachandran P, Craig T, Atanasova E, Cui G, Owen B, Bergen 3rd H, et al.
J Biol Chem
. 2012 Sep;
287(47):39439-48.
PMID: 23019329
Downstream regulatory element antagonistic modulator (DREAM/KChIP3), a neuronal EF-hand protein, modulates pain, potassium channel activity, and binds presenilin 1. Using affinity capture of neuronal proteins by immobilized DREAM/KChIP3 in the...
16.
Craig T, Zhang Y, McNulty M, Middha S, Ketha H, Singh R, et al.
Mol Endocrinol
. 2012 Jun;
26(9):1630-42.
PMID: 22734042
The biological role of vitamin D receptors (VDR), which are abundantly expressed in developing zebrafish (Danio rerio) as early as 48 h after fertilization, and before the development of a...
17.
McNulty M, Bedell V, Greenwood T, Craig T, Ekker S, Kumar R
Gene Expr Patterns
. 2012 May;
12(7-8):228-35.
PMID: 22575304
Sclerostin is a highly conserved, secreted, cystine-knot protein which regulates osteoblast function. Humans with mutations in the sclerostin gene (SOST), manifest increased axial and appendicular skeletal bone density with attendant...
18.
Devarajan-Ketha H, Craig T, Madden B, Bergen 3rd H, Kumar R
Biochem Biophys Res Commun
. 2011 Dec;
417(2):830-5.
PMID: 22206666
The secreted glycoprotein, sclerostin alters bone formation. To gain insights into the mechanism of action of sclerostin, we examined the interactions of sclerostin with bone proteins using a sclerostin affinity...
19.
Craig T, Kumar R
Biochem Biophys Res Commun
. 2010 Oct;
402(2):421-4.
PMID: 20951118
To gain insights into the mechanism of action of sclerostin, a protein that regulates bone mass, we performed yeast two-hybrid analyses using human SOST (sclerostin) cDNA cloned into pGBKT7 DNA-binding...
20.
Craig T, Bhattacharya R, Mukhopadhyay D, Kumar R
Biochem Biophys Res Commun
. 2010 Jan;
392(1):36-40.
PMID: 20043874
Sclerostin, a secreted glycoprotein, regulates osteoblast function. Using yeast two-hybrid and direct protein interaction analyses, we demonstrate that sclerostin binds the Wnt-modulating and Wnt-modulated, extracellular matrix protein, cysteine-rich protein 61...