H Robert Bergen 3rd
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Explore the profile of H Robert Bergen 3rd including associated specialties, affiliations and a list of published articles.
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47
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1502
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Recent Articles
1.
Tischer A, Brehm M, Machha V, Moon-Tasson L, Benson L, Nelton K, et al.
J Mol Biol
. 2019 Oct;
432(2):305-323.
PMID: 31628947
Von Willebrand factor (VWF), an exceptionally large multimeric plasma glycoprotein, functions to initiate coagulation by agglutinating platelets in the blood stream to sites of vascular injury. This primary hemostatic function...
2.
Andrich K, Hegenbart U, Kimmich C, Kedia N, Bergen 3rd H, Schonland S, et al.
J Biol Chem
. 2016 Dec;
292(6):2328-2344.
PMID: 28031465
Intervention into amyloid deposition with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (AL). In both AL and...
3.
Zhai X, Gao Y, Mishra S, Simanshu D, Boldyrev I, Benson L, et al.
J Biol Chem
. 2016 Dec;
292(6):2531-2541.
PMID: 28011644
Genetic models for studying localized cell suicide that halt the spread of pathogen infection and immune response activation in plants include mutant (). In this mutant, sphingolipid homeostasis is disrupted...
4.
Robinson M, Dasari S, Karakelides H, Bergen 3rd H, Nair K
Am J Physiol Endocrinol Metab
. 2016 Jul;
311(3):E628-37.
PMID: 27436610
Insulin regulates skeletal muscle protein degradation, but the types of proteins being degraded in vivo remain to be determined due to methodological limitations. We present a method to assess the...
5.
Schafer M, Atkinson E, Vanderboom P, Kotajarvi B, White T, Moore M, et al.
Cell Metab
. 2016 Jun;
23(6):1207-1215.
PMID: 27304512
Growth and differentiation factor 11 (GDF11) is a transforming growth factor β superfamily member with a controversial role in aging processes. We have developed a highly specific LC-MS/MS assay to...
6.
Zabielski P, Lanza I, Gopala S, Heppelmann C, Bergen 3rd H, Dasari S, et al.
Diabetes
. 2016 Jan;
65(3):561-73.
PMID: 26718503
Insulin plays pivotal role in cellular fuel metabolism in skeletal muscle. Despite being the primary site of energy metabolism, the underlying mechanism on how insulin deficiency deranges skeletal muscle mitochondrial...
7.
Bergen 3rd H, Dasari S, Dispenzieri A, Mills J, Ramirez-Alvarado M, Tschumper R, et al.
Clin Chem
. 2015 Oct;
62(1):243-51.
PMID: 26430073
Background: Analytically sensitive techniques for measuring minimal residual disease (MRD) in multiple myeloma (MM) currently require invasive and costly bone marrow aspiration. These methods include immunohistochemistry (IHC), flow cytometry, quantitative...
8.
Bergen 3rd H, Farr J, Vanderboom P, Atkinson E, White T, Singh R, et al.
Skelet Muscle
. 2015 Jul;
5:21.
PMID: 26180626
Background: Myostatin is a protein synthesized and secreted by skeletal muscle that negatively regulates muscle mass. The extent to which circulating myostatin levels change in the context of aging is...
9.
Zhu Y, Tchkonia T, Stout M, Giorgadze N, Wang L, Li P, et al.
Obesity (Silver Spring)
. 2015 Apr;
23(5):989-99.
PMID: 25864718
Objective: Visceral white adipose tissue (WAT) expansion and macrophage accumulation are associated with metabolic dysfunction. Visceral WAT typically shows greater macrophage infiltration. Preadipocytes show varying proinflammatory expression profiles among WAT...
10.
Johnson M, Irving B, Lanza I, Vendelbo M, Konopka A, Robinson M, et al.
J Gerontol A Biol Sci Med Sci
. 2014 Dec;
70(11):1386-93.
PMID: 25504576
Acute aerobic exercise increases reactive oxygen species and could potentially damage proteins, but exercise training (ET) enhances mitochondrial respiration irrespective of age. Here, we report a differential impact of ET...