Thekla Cordes
Overview
Explore the profile of Thekla Cordes including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
1729
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Recent Articles
1.
Greene T, Jo Y, Chiale C, Macal M, Fang Z, Khatri F, et al.
Nat Commun
. 2025 Feb;
16(1):1460.
PMID: 39920132
Type I Interferons (IFN-I) are central to host protection against viral infections, with plasmacytoid dendritic cells (pDC) being the most significant source, yet pDCs lose their IFN-I production capacity following...
2.
Willenbockel H, Williams A, Lucas A, Dowerg B, Cabrales P, Metallo C, et al.
bioRxiv
. 2025 Jan;
PMID: 39803428
Itaconate is an immunomodulatory metabolite that alters mitochondrial metabolism and immune cell function. This organic acid is endogenously synthesized via tricarboxylic acid (TCA) metabolism downstream of TLR signaling. Itaconate-based treatment...
3.
4.
Willenbockel H, Dowerg B, Cordes T
Curr Opin Biotechnol
. 2024 Aug;
89:103183.
PMID: 39197341
The impact of bacteria and viruses on tumor growth has long been recognized. In recent decades, interest in the role of microorganisms in the tumor microenvironment (TME) has expanded. Infections...
5.
Frederick M, Nassef M, Borrelli M, Kuang S, Buensuceso A, More T, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Jun;
1870(7):167312.
PMID: 38901649
Epithelial ovarian cancer (EOC) is highly lethal due to its unique metastatic characteristics. EOC spheroids enter a non-proliferative state, with hypoxic cores and reduced oncogenic signaling, all of which contribute...
6.
Parker S, Cordes T
Curr Opin Biotechnol
. 2024 Mar;
87:103095.
PMID: 38520823
No abstract available.
7.
Greene T, Jo Y, Macal M, Fang Z, Khatri F, Codrington A, et al.
bioRxiv
. 2024 Mar;
PMID: 38464328
Type I Interferons (IFN-I) are central to host protection against viral infections . While any cell can produce IFN-I, Plasmacytoid Dendritic Cells (pDCs) make greater quantities and more varieties of...
8.
Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna R, Traina K, Robles-Oteiza C, et al.
Cancer Discov
. 2024 Jan;
:OF1-OF22.
PMID: 38270272
Significance: Alternate strategies harnessing anticancer innate immunity are required for lung cancers with poor response rates to T cell-based immunotherapies. This study identifies a targetable, mutually supportive, metabolic relationship between...
9.
Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna R, Traina K, Robles-Oteiza C, et al.
Cancer Discov
. 2024 Jan;
PMID: 38241033
The limited efficacy of currently approved immunotherapies in EGFR-driven lung adenocarcinoma (LUAD) underscores the need to better understand alternative mechanisms governing local immunosuppression to fuel novel therapies. Elevated surfactant and...
10.
Muta Y, Linares J, Martinez-Ordonez A, Duran A, Cid-Diaz T, Kinoshita H, et al.
Nat Commun
. 2023 Dec;
14(1):8075.
PMID: 38092754
The metabolic and signaling pathways regulating aggressive mesenchymal colorectal cancer (CRC) initiation and progression through the serrated route are largely unknown. Although relatively well characterized as BRAF mutant cancers, their...