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Tejashri Chavan

Explore the profile of Tejashri Chavan including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 32
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Recent Articles
1.
Chavan T, Kanabar D, Patel K, Laflamme T, Riyazi M, Spratt D, et al.
Bioorg Med Chem . 2024 Jul; 110:117836. PMID: 39029437
Liver cancer is a complex disease that involves various oncoproteins and the inactivation of tumor suppressor proteins (TSPs). Gankyrin is one such oncoprotein, first identified in human hepatocellular carcinoma, that...
2.
Kanabar D, Kane E, Chavan T, Laflamme T, Suarez E, Goyal M, et al.
Future Med Chem . 2024 Jan; 16(3):239-251. PMID: 38205637
Gankyrin is an ankyrin-repeat protein that promotes cell proliferation, tumor development and cancer progression when overexpressed. To design and synthesize a novel series of gankyrin-binding small molecules predicated on a...
3.
Patil S, Barji D, Chavan T, Patel K, Collazo A, Prithipaul V, et al.
AAPS PharmSciTech . 2023 Jan; 24(1):49. PMID: 36702977
Tuberculosis (TB) is a contiguous airborne disease caused by Mycobacterium tuberculosis (M.tb), primarily affecting the human lungs. The progression of drug-susceptible TB to drug-resistant strains, MDR-TB and XDR-TB, has become...
4.
Kanabar D, Goyal M, Kane E, Chavan T, Kabir A, Wang X, et al.
J Med Chem . 2022 Jun; 65(13):8975-8997. PMID: 35758870
Gankyrin is an oncoprotein responsible for the development of numerous cancer types. It regulates the expression levels of multiple tumor suppressor proteins (TSPs) in liver cancer; however, gankyrin's regulation of...
5.
Chavan T, Muth A
Future Med Chem . 2021 Aug; 13(19):1679-1694. PMID: 34410182
α-Mangostin is a xanthone natural product isolated as a secondary metabolite from the mangosteen tree. It has attracted a great deal of attention due to its wide-ranging effects on certain...
6.
Parvathaneni V, Elbatanony R, Goyal M, Chavan T, Vega N, Kolluru S, et al.
Int J Mol Sci . 2021 May; 22(9). PMID: 33946414
There is growing evidence that repurposed drugs demonstrate excellent efficacy against many cancers, while facilitating accelerated drug development process. In this study, bedaquiline (BDQ), an FDA approved anti-mycobacterial agent, was...
7.
Kanabar D, Kabir A, Chavan T, Kong J, Yoganathan S, Muth A
Bioorg Med Chem Lett . 2021 Apr; 43:128043. PMID: 33865970
No abstract available.
8.
Tawfeek H, Chavan T, Kunda N
AAPS PharmSciTech . 2020 Jul; 21(5):181. PMID: 32607628
Cocrystals have gained a lot of consideration regarding its superior role in enhancement of solubility and dissolution of the included API. Cocrystals could be converted to coamorphous systems via different...