Tatsuya Tsukui
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Explore the profile of Tatsuya Tsukui including associated specialties, affiliations and a list of published articles.
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27
Citations
947
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Recent Articles
1.
Fang Y, Chung S, Xu L, Xue C, Liu X, Jiang D, et al.
Nature
. 2025 Feb;
PMID: 39910313
A hallmark of pulmonary fibrosis is the aberrant activation of lung fibroblasts into pathological fibroblasts that produce excessive extracellular matrix. Thus, the identification of key regulators that promote the generation...
2.
Khan I, Molina C, Ren X, Auyeung V, Cohen M, Tsukui T, et al.
Elife
. 2024 Dec;
13.
PMID: 39660606
Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD,...
3.
Yadav P, Ortega J, Tamaki W, Chien C, Chang K, Biswas N, et al.
bioRxiv
. 2024 Aug;
PMID: 39211079
Monocyte-derived macrophages recruited to injured tissues induce a maladaptive fibrotic response characterized by excessive production of collagen by local fibroblasts. Macrophages initiate this programming via paracrine factors, but it is...
4.
Tsukui T, Wolters P, Sheppard D
Nature
. 2024 Jul;
631(8021):627-634.
PMID: 38987592
Fibroblasts are present throughout the body and function to maintain tissue homeostasis. Recent studies have identified diverse fibroblast subsets in healthy and injured tissues, but the origins and functional roles...
5.
Lee J, Reyes N, Ravishankar S, Zhou M, Krasilnikov M, Ringler C, et al.
J Clin Invest
. 2024 Mar;
134(9).
PMID: 38451724
The appearance of senescent cells in age-related diseases has spurred the search for compounds that can target senescent cells in tissues, termed senolytics. However, a major caveat with current senolytic...
6.
Khan I, Molina C, Ren X, Auyeung V, Cohen M, Tsukui T, et al.
bioRxiv
. 2024 Jan;
PMID: 38187712
Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD,...
7.
Zhang J, Tsukui T, Wu X, Brito A, Trumble J, Caraballo J, et al.
Life Sci Alliance
. 2023 Jun;
6(8).
PMID: 37311583
Immunological targeting of pathological cells has been successful in oncology and is expanding to other pathobiological contexts. Here, we present a flexible platform that allows labeling cells of interest with...
8.
Nishida J, Shichino S, Tsukui T, Hoshino M, Okada T, Okada K, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743163
Mucin 21(Muc21)/epiglycanin is expressed on apical surfaces of squamous epithelia and has potentially protective roles, which are thought to be associated with its unique glycoforms, whereas its aberrant glycosylation is...
9.
Bhattacharyya A, Torre P, Yadav P, Boostanpour K, Chen T, Tsukui T, et al.
Front Immunol
. 2022 May;
13:880887.
PMID: 35634278
Macrophages are paracrine signalers that regulate tissular responses to injury through interactions with parenchymal cells. Connexin hemichannels have recently been shown to mediate efflux of ATP by macrophages, with resulting...
10.
Tian Y, Denda-Nagai K, Tsukui T, Ishii-Schrade K, Okada K, Nishizono Y, et al.
Cell Death Discov
. 2022 Apr;
8(1):194.
PMID: 35410995
Highly glycosylated mucins protect epithelial surfaces from external insults and are related to malignant behaviors of carcinoma cells. However, the importance of carbohydrate chains on mucins in the process of...