Tatsuhisa Tsuboi
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Explore the profile of Tatsuhisa Tsuboi including associated specialties, affiliations and a list of published articles.
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10
Citations
251
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Recent Articles
1.
Khan A, Gu X, Patel R, Chuphal P, Viana M, Brown A, et al.
Nat Commun
. 2024 Sep;
15(1):8274.
PMID: 39333462
A decline in mitochondrial function is a hallmark of aging and neurodegenerative diseases. It has been proposed that changes in mitochondrial morphology, including fragmentation of the tubular mitochondrial network, can...
2.
Ma J, Tsuboi T
Methods Mol Biol
. 2024 Mar;
2784:191-200.
PMID: 38502487
The secondary and tertiary structures of RNA play a vital role in the regulation of biological reactions. These structures have been experimentally studied through in vivo and in vitro analyses,...
3.
Liu L, Fan X, Lu Q, Wang P, Wang X, Han Y, et al.
Int J Biol Macromol
. 2024 Jan;
260(Pt 1):129251.
PMID: 38211908
Reactive oxygen species (ROS) play an important role in biological milieu. Recently, the rapid growth in our understanding of ROS and their promise in antibacterial applications has generated tremendous interest...
4.
Guo T, Modi O, Hirano J, Guzman H, Tsuboi T
Biophys Rep (N Y)
. 2022 Nov;
2(3):100065.
PMID: 36425329
The three-dimensional conformation of RNA is important in the function and fate of the molecule. The common conformation of mRNA is formed based on the closed-loop structure and internal base...
5.
Tsuboi T, Leff J, Zid B
Biochem Soc Trans
. 2020 Nov;
48(6):2565-2578.
PMID: 33245320
In fluctuating environmental conditions, organisms must modulate their bioenergetic production in order to maintain cellular homeostasis for optimal fitness. Mitochondria are hubs for metabolite and energy generation. Mitochondria are also...
6.
Tsuboi T, Viana M, Xu F, Yu J, Chanchani R, Arceo X, et al.
Elife
. 2020 Aug;
9.
PMID: 32762840
Mitochondria are dynamic organelles that must precisely control their protein composition according to cellular energy demand. Although nuclear-encoded mRNAs can be localized to the mitochondrial surface, the importance of this...
7.
Tsuboi T, Yamazaki R, Nobuta R, Ikeuchi K, Makino S, Ohtaki A, et al.
J Biol Chem
. 2015 May;
290(26):16021-30.
PMID: 25971974
The tRNA splicing endonuclease (Sen) complex is located on the mitochondrial outer membrane and splices precursor tRNAs in Saccharomyces cerevisiae. Here, we demonstrate that the Sen complex cleaves the mitochondria-localized...
8.
Izawa T, Tsuboi T, Kuroha K, Inada T, Nishikawa S, Endo T
Cell Rep
. 2012 Sep;
2(3):447-53.
PMID: 22981232
Because messenger RNAs without a stop codon (nonstop mRNAs) generate stalled ribosomes, cells have developed a mechanism allowing degradation of nonstop mRNAs and their translation products (nonstop proteins) in the...
9.
Tsuboi T, Kuroha K, Kudo K, Makino S, Inoue E, Kashima I, et al.
Mol Cell
. 2012 Apr;
46(4):518-29.
PMID: 22503425
Translation arrest leads to an endonucleolytic cleavage of mRNA that is termed no-go decay (NGD). It has been reported that the Dom34:Hbs1 complex stimulates this endonucleolytic cleavage of mRNA induced...
10.
Tsuboi T, Inada T
J Biol Chem
. 2010 Aug;
285(44):33589-601.
PMID: 20732870
The decay of eukaryotic mRNA is triggered mainly by deadenylation, which leads to decapping and degradation from the 5' end of an mRNA. Poly(A)-binding protein has been proposed to inhibit...