Shiho Makino
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Explore the profile of Shiho Makino including associated specialties, affiliations and a list of published articles.
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9
Citations
233
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Recent Articles
1.
Makino S, Fukaya T
Bioessays
. 2024 Jun;
46(9):e2400101.
PMID: 38922969
Enhancers are short segments of regulatory DNA that control when and in which cell-type genes should be turned on in response to a variety of extrinsic and intrinsic signals. At...
2.
Hamamoto K, Umemura Y, Makino S, Fukaya T
Nat Commun
. 2023 Feb;
14(1):826.
PMID: 36805453
Non-coding transcription at the intergenic regulatory regions is a prevalent feature of metazoan genomes, but its biological function remains uncertain. Here, we devise a live-imaging system that permits simultaneous visualization...
3.
Kawamata T, Makino S, Kagohashi Y, Sasaki M, Ohsumi Y
J Biol Chem
. 2022 Oct;
298(12):102641.
PMID: 36306824
Autophagy is a major cellular degradation pathway that is highly conserved among eukaryotes. The identification of cargos captured by autophagosomes is critical to our understanding of the physiological significance of...
4.
Makino S, Kawamata T, Iwasaki S, Ohsumi Y
Nat Commun
. 2021 Apr;
12(1):2316.
PMID: 33875662
Synthesis and degradation of cellular constituents must be balanced to maintain cellular homeostasis, especially during adaptation to environmental stress. The role of autophagy in the degradation of proteins and organelles...
5.
Tsuboi T, Yamazaki R, Nobuta R, Ikeuchi K, Makino S, Ohtaki A, et al.
J Biol Chem
. 2015 May;
290(26):16021-30.
PMID: 25971974
The tRNA splicing endonuclease (Sen) complex is located on the mitochondrial outer membrane and splices precursor tRNAs in Saccharomyces cerevisiae. Here, we demonstrate that the Sen complex cleaves the mitochondria-localized...
6.
Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast
Makino S, Mishima Y, Inoue K, Inada T
J Biol Chem
. 2015 Feb;
290(13):8331-47.
PMID: 25657010
The CCR4-NOT complex, the major deadenylase in eukaryotes, plays crucial roles in gene expression at the levels of transcription, mRNA decay, and protein degradation. GW182/TNRC6 proteins, which are core components...
7.
Inada T, Makino S
Front Genet
. 2014 Jun;
5:135.
PMID: 24904636
The CCR4-NOT complex is a highly conserved specific gene silencer that also serves more general post-transcriptional functions. Specific regulatory proteins including the miRNA-induced silencing complex and its associated proteins, bind...
8.
Tsuboi T, Kuroha K, Kudo K, Makino S, Inoue E, Kashima I, et al.
Mol Cell
. 2012 Apr;
46(4):518-29.
PMID: 22503425
Translation arrest leads to an endonucleolytic cleavage of mRNA that is termed no-go decay (NGD). It has been reported that the Dom34:Hbs1 complex stimulates this endonucleolytic cleavage of mRNA induced...
9.
Sugimoto Y, Makino S, Doi Y, Nishimura M, Baba M, Mizukawa S, et al.
Masui
. 2009 Feb;
58(2):209-11.
PMID: 19227180
We report a case of conversion disorder after spinal anesthesia. A 16-year-old healthy woman underwent arthroscopic surgery under spinal anesthesia. She showed tremor all over and it did not stop....