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Tanecia Mitchell

Explore the profile of Tanecia Mitchell including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Crivelli J, Mitchell T, Knight J, Wood K, Assimos D, Holmes R, et al.
Nutrients . 2020 Dec; 13(1). PMID: 33379176
Kidney stone disease is increasing in prevalence, and the most common stone composition is calcium oxalate. Dietary oxalate intake and endogenous production of oxalate are important in the pathophysiology of...
12.
Kumar P, Patel M, Thomas V, Knight J, Holmes R, Mitchell T
Kidney Int Rep . 2020 Jul; 5(7):1040-1051. PMID: 32647761
Introduction: Crystalluria is thought to be associated with kidney stone formation and can occur when urine becomes supersaturated with calcium, oxalate, and phosphate. The principal method used to identify urinary...
13.
Kundu A, Nam H, Shelar S, Chandrashekar D, Brinkley G, Karki S, et al.
J Exp Med . 2020 Apr; 217(6). PMID: 32251515
Analysis of transcriptomic data demonstrates extensive epigenetic gene silencing of the transcription factor PRDM16 in renal cancer. We show that restoration of PRDM16 in RCC cells suppresses in vivo tumor...
14.
Mitchell T, De Miguel C, Gohar E
Redox Biol . 2020 Mar; 31:101489. PMID: 32197946
Sex differences in redox signaling in the kidney present new challenges and opportunities for understanding the physiology and pathophysiology of the kidney. This review will focus on reactive oxygen species,...
15.
Mitchell T, Kumar P, Reddy T, Wood K, Knight J, Assimos D, et al.
Am J Physiol Renal Physiol . 2018 Dec; 316(3):F409-F413. PMID: 30566003
Dietary oxalate is plant-derived and may be a component of vegetables, nuts, fruits, and grains. In normal individuals, approximately half of urinary oxalate is derived from the diet and half...
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Patel M, Yarlagadda V, Adedoyin O, Saini V, Assimos D, Holmes R, et al.
Redox Biol . 2017 Dec; 15:207-215. PMID: 29272854
Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the...
18.
Chacko B, Wall S, Kramer P, Ravi S, Mitchell T, Johnson M, et al.
Redox Biol . 2016 Jul; 9:57-66. PMID: 27393890
Metabolic control of cellular function is significant in the context of inflammation-induced metabolic dysregulation in immune cells. Generation of reactive oxygen species (ROS) such as hydrogen peroxide and superoxide are...
19.
Williams J, Holmes R, Assimos D, Mitchell T
Urology . 2016 Mar; 93:224.e1-6. PMID: 26972146
Objective: To investigate whether mitochondrial function is altered in circulating immune cells from calcium oxalate (CaOx) stone formers compared to healthy subjects. Materials And Methods: Adult healthy subjects (n = ...
20.
Chacko B, Zhi D, Darley-Usmar V, Mitchell T
Redox Biol . 2016 Jan; 8:43-50. PMID: 26748041
Metabolic and bioenergetic dysfunction are associated with oxidative stress and thought to be a common underlying mechanism of chronic diseases such as atherosclerosis, diabetes, and neurodegeneration. Recent findings support an...