Philip A Kramer
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Explore the profile of Philip A Kramer including associated specialties, affiliations and a list of published articles.
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39
Citations
1181
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Recent Articles
1.
Mau T, Blackwell T, Cawthon P, Molina A, Coen P, Distefano G, et al.
medRxiv
. 2024 Dec;
PMID: 39711735
Background: The geroscience hypothesis posits that aging biological processes contribute to many age-related deficits, including the accumulation of multiple chronic diseases. Though only one facet of mitochondrial function, declines in...
2.
Gay E, Coen P, Harrison S, Garcia R, Qiao Y, Goodpaster B, et al.
Geroscience
. 2024 Oct;
PMID: 39436549
Greater perceived physical fatigability and lower skeletal muscle energetics are both predictors of mobility decline. Characterizing associations between muscle energetics and perceived fatigability may provide insight into potential targets to...
3.
Distefano G, Harrison S, Lynch J, Link T, Kramer P, Ramos S, et al.
Arthritis Rheumatol
. 2024 Jul;
76(12):1764-1774.
PMID: 39016102
Objective: Our objective was to investigate the overall and sex-specific relationships between the presence and severity of knee osteoarthritis (KOA) and muscle composition, power, and energetics in older adults. Methods:...
4.
Gay E, Coen P, Harrison S, Garcia R, Qiao Y, Goodpaster B, et al.
medRxiv
. 2024 Jun;
PMID: 38853946
Greater perceived physical fatigability and lower skeletal muscle energetics are predictors of mobility decline. Characterizing associations between muscle energetics and perceived fatigability may provide insight into potential targets to prevent...
5.
Tranah G, Barnes H, Cawthon P, Coen P, Esser K, Hepple R, et al.
Aging Cell
. 2024 Jun;
23(6):e14114.
PMID: 38831629
Gene expression in skeletal muscle of older individuals may reflect compensatory adaptations in response to oxidative damage that preserve tissue integrity and maintain function. Identifying associations between oxidative stress response...
6.
Brennan A, Coen P, Mau T, Hetherington-Rauth M, Toledo F, Kershaw E, et al.
Obesity (Silver Spring)
. 2024 May;
32(6):1125-1135.
PMID: 38803308
Objective: The aim of this study was to examine associations of ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. Methods: Cross-sectional data from 829 adults...
7.
Mau T, Blackwell T, Cawthon P, Molina A, Coen P, Distefano G, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Apr;
79(7).
PMID: 38605684
Background: The geroscience hypothesis posits that aging biological processes contribute to many age-related deficits, including the accumulation of multiple chronic diseases. Though only one facet of mitochondrial function, declines in...
8.
Duchowny K, Marcinek D, Mau T, Diaz-Ramierz L, Lui L, Toledo F, et al.
Sci Adv
. 2024 Mar;
10(10):eadj6411.
PMID: 38446898
Social stress experienced in childhood is associated with adverse health later in life. Mitochondrial function has been implicated as a mechanism for how stressful life events "get under the skin"...
9.
Day N, Kelly S, Lui L, Mansfield T, Gaffrey M, Trejo J, et al.
Aging Cell
. 2024 Feb;
23(6):e14094.
PMID: 38332629
Oxidative stress is considered a contributor to declining muscle function and mobility during aging; however, the underlying molecular mechanisms remain poorly described. We hypothesized that greater levels of cysteine (Cys)...
10.
Kramer P, Zamora E, Barnes H, Strotmeyer E, Glynn N, Lane N, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Jan;
79(4.
PMID: 38206375
Background: Falls in the older population are a major public health concern. While many physiological and environmental factors have been associated with fall risk, muscle mitochondrial energetics has not yet...