Tal Ben-Yishay
Overview
Explore the profile of Tal Ben-Yishay including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
5
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0
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Recent Articles
1.
Haj M, Frey Y, Levon A, Maliah A, Ben-Yishay T, Slutsky R, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(2):e2419196122.
PMID: 39772747
Ataxia-telangiectasia (A-T) is a pleiotropic genome instability syndrome resulting from the loss of the homeostatic protein kinase ATM. The complex phenotype of A-T includes progressive cerebellar degeneration, immunodeficiency, gonadal atrophy,...
2.
Sdeor E, Okada H, Saad R, Ben-Yishay T, Ben-David U
Nat Genet
. 2024 Oct;
56(10):2014-2026.
PMID: 39358600
Aneuploidy, an abnormal chromosome composition, is a major contributor to cancer development and progression and an important determinant of cancer therapeutic responses and clinical outcomes. Despite being recognized as a...
3.
Ippolito M, Zerbib J, Eliezer Y, Reuveni E, Vigano S, De Feudis G, et al.
Cancer Discov
. 2024 Sep;
14(12):2532-2553.
PMID: 39247952
Aneuploidy results in a stoichiometric imbalance of protein complexes that jeopardizes cellular fitness. Aneuploid cells thus need to compensate for the imbalanced DNA levels by regulating their RNA and protein...
4.
Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko G, Gunn A, et al.
Science
. 2024 Aug;
385(6712):eadj7446.
PMID: 39208097
Chromosomal instability (CIN) generates micronuclei-aberrant extranuclear structures that catalyze the acquisition of complex chromosomal rearrangements present in cancer. Micronuclei are characterized by persistent DNA damage and catastrophic nuclear envelope collapse,...