» Authors » Simone Scorzoni

Simone Scorzoni

Explore the profile of Simone Scorzoni including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 3
Citations 10
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Zerbib J, Ippolito M, Eliezer Y, De Feudis G, Reuveni E, Savir Kadmon A, et al.
Nat Commun . 2024 Sep; 15(1):7772. PMID: 39251587
Aneuploidy is a hallmark of human cancer, yet the molecular mechanisms to cope with aneuploidy-induced cellular stresses remain largely unknown. Here, we induce chromosome mis-segregation in non-transformed RPE1-hTERT cells and...
2.
Ippolito M, Zerbib J, Eliezer Y, Reuveni E, Vigano S, De Feudis G, et al.
Cancer Discov . 2024 Sep; 14(12):2532-2553. PMID: 39247952
Aneuploidy results in a stoichiometric imbalance of protein complexes that jeopardizes cellular fitness. Aneuploid cells thus need to compensate for the imbalanced DNA levels by regulating their RNA and protein...
3.
Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko G, Gunn A, et al.
Science . 2024 Aug; 385(6712):eadj7446. PMID: 39208097
Chromosomal instability (CIN) generates micronuclei-aberrant extranuclear structures that catalyze the acquisition of complex chromosomal rearrangements present in cancer. Micronuclei are characterized by persistent DNA damage and catastrophic nuclear envelope collapse,...