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Takeshi Ego

Explore the profile of Takeshi Ego including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 121
Followers 0
Related Specialties
Oncology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Kunitada Shimotohno
Yasuo Ariumi
Tadaaki Ohgi
Junko Homan
Haruna Naruoka
Kouichi Ishiyama
Kazuchika Takagaki
Kazuya Kuramoto
Junji Sagara
Sa Xiao
Published In
Oncogene
J Biol Chem
Microbiol Immunol
Anticancer Res
Nucleic Acids Res
Affiliations
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Recent Articles
1.
Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1
Kimura S, Kuramoto K, Homan J, Naruoka H, Ego T, Nogawa M, et al.
Anticancer Res . 2012 Mar; 32(3):795-8. PMID: 22399596
Background: The myelodysplastic syndromes (MDS) are a group of stem cell disorders characterized by dysplasia of one or more hematopoietic cell lineages and a risk of progression to acute myeloid...
2.
BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3
Hishiki T, Ohshima T, Ego T, Shimotohno K
J Biol Chem . 2007 Jul; 282(39):28335-28343. PMID: 17644518
By associating with cyclic AMP-responsive element-binding protein (CREB), the human T-cell leukemia virus type 1 (HTLV-1) Tax protein activates transcription from the HTLV-1 long terminal repeat (LTR), which contains multiple...
3.
Chemical synthesis of a very long oligoribonucleotide with 2-cyanoethoxymethyl (CEM) as the 2'-O-protecting group: structural identification and biological activity of a synthetic 110mer precursor-microRNA candidate
Shiba Y, Masuda H, Watanabe N, Ego T, Takagaki K, Ishiyama K, et al.
Nucleic Acids Res . 2007 Apr; 35(10):3287-96. PMID: 17459888
A long RNA oligomer, a 110mer with the sequence of a precursor-microRNA candidate, has been chemically synthesized in a single synthesizer run by means of standard automated phosphoramidite chemistry. The...
4.
Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR
Ego T, Tanaka Y, Shimotohno K
Oncogene . 2005 Jan; 24(11):1914-23. PMID: 15674330
Epigenetic regulation of gene expression is critical in the maintenance of cellular homeostasis. Dysregulation of normal epigenetic transcription occurs in abnormal physiological conditions, such as those seen in cancer cells...
5.
Further characterization of a CD99-related 21-kDa transmembrane protein (VAP21) expressed in Syrian hamster cells and its possible involvement in vesicular stomatitis virus production
Tochikura T, Xiao S, Ego T, Sagara J, Kawai A
Microbiol Immunol . 2003 Nov; 47(10):745-57. PMID: 14605441
The VAP21, a CD99-related 21-kDa transmembrane protein, was first detected in the enveloped virions that were grown in a Syrian hamster-derived cell line, BHK-21 (Sagara et al., 1997; Yamamoto et...
6.
Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein
Ariumi Y, Ego T, Kaida A, Matsumoto M, Pandolfi P, Shimotohno K
Oncogene . 2003 Mar; 22(11):1611-9. PMID: 12642864
Several viruses target cellular promyelocytic leukemia (PML)-nuclear bodies (PML-NBs) to induce their disruption, marked morphological changes in these structures or the relocation to PML-NB components to the cytoplasm of infected...
7.
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression
Ego T, Ariumi Y, Shimotohno K
Oncogene . 2002 Oct; 21(47):7241-6. PMID: 12370815
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are known to interact with several transcription factors and regulate their transcriptional activities. The human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein...