Junji Sagara
Overview
Explore the profile of Junji Sagara including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
2030
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0
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Recent Articles
1.
Kawakubo M, Horiuchi K, Matsumoto T, Nakayama J, Akamatsu T, Katsuyama T, et al.
Helicobacter
. 2017 Nov;
23(1).
PMID: 29110387
Background: Non-Helicobacter pylori helicobacters (NHPHs) besides H. pylori infect human stomachs and cause chronic gastritis and mucosa-associated lymphoid tissue lymphoma. Cholesteryl-α-glucosides have been identified as unique glycolipids present in H. ...
2.
Kawakubo M, Horiuchi K, Komura H, Sato Y, Kato M, Ikeyama M, et al.
Histochem Cell Biol
. 2017 May;
148(4):463-471.
PMID: 28534071
Helicobacter suis (H. suis), formerly called Helicobacter heilmannii type 1 (H. heilmannii), is a gram-negative bacterium of the Helicobacter species. This pathogen infects the stomach of humans and animals such...
3.
Kang S, Fernandes-Alnemri T, Rogers C, Mayes L, Wang Y, Dillon C, et al.
Nat Commun
. 2015 Jun;
6:7515.
PMID: 26104484
TLR2 promotes NLRP3 inflammasome activation via an early MyD88-IRAK1-dependent pathway that provides a priming signal (signal 1) necessary for activation of the inflammasome by a second potassium-depleting signal (signal 2)....
4.
Karasawa T, Kawashima A, Usui F, Kimura H, Shirasuna K, Inoue Y, et al.
FEBS Open Bio
. 2015 May;
5:348-56.
PMID: 25973362
Increasing evidence indicates that caspase recruitment domain (CARD)-mediated caspase-1 (CASP1) assembly is an essential process for its activation and subsequent interleukin (IL)-1β release, leading to the initiation of inflammation. Both...
5.
Itoh A, Uchiyama A, Taniguchi S, Sagara J
PLoS One
. 2014 Nov;
9(11):e113289.
PMID: 25405772
Proteins that belong to the protein phosphatase 1 and actin regulator (phactr) family are involved in cell motility and morphogenesis. However, the mechanisms that regulate the actin cytoskeleton are poorly...
6.
Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, et al.
Arterioscler Thromb Vasc Biol
. 2014 Nov;
35(1):127-36.
PMID: 25378412
Objective: Abdominal aortic aneurysm (AAA) is considered a chronic inflammatory disease; however, the molecular basis underlying the sterile inflammatory response involved in the process of AAA remains unclear. We previously...
7.
Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, et al.
Nanotoxicology
. 2014 Sep;
9(5):554-67.
PMID: 25211550
Despite the increasing commercial use of nanoparticles, little is known about their effects on placental inflammation and pregnancy complications. In this study, nanosilica (NS) particles upregulated the inflammasome component nucleotide-binding...
8.
Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, et al.
J Immunol
. 2014 Apr;
192(9):4342-51.
PMID: 24696236
Inflammation plays a key role in the pathophysiology of hepatic ischemia-reperfusion (I/R) injury. However, the mechanism by which hepatic I/R induces inflammatory responses remains unclear. Recent evidence indicates that a...
9.
Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, et al.
Am J Pathol
. 2014 Mar;
184(5):1287-98.
PMID: 24606883
Inflammation plays a crucial role in the pathophysiological characteristics of chronic kidney disease; however, the inflammatory mechanisms underlying the chronic kidney disease process remain unclear. Recent evidence indicates that sterile...
10.
Fernandes-Alnemri T, Kang S, Anderson C, Sagara J, Fitzgerald K, Alnemri E
J Immunol
. 2013 Sep;
191(8):3995-9.
PMID: 24043892
Activation of the NLRP3 inflammasome by diverse stimuli requires a priming signal from TLRs and an activation signal from purinergic receptors or pore-forming toxins. In this study, we demonstrate, through...