Tai Young Kim
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Explore the profile of Tai Young Kim including associated specialties, affiliations and a list of published articles.
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44
Citations
987
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Recent Articles
1.
Kim J, Kim T, Son S, Kim S, Kwon J, Kwon H, et al.
Plants (Basel)
. 2024 Jan;
13(2).
PMID: 38276760
Triterpenoidal saponins have been reported to be able to restrain SARS-CoV-2 infection. To isolate antiviral compounds against SARS-CoV-2 from the leaves of , we conducted multiple steps of column chromatography....
2.
Diep Y, Park H, Kwon J, Tran M, Ko H, Jo H, et al.
Biomater Res
. 2023 Jul;
27(1):71.
PMID: 37468961
Background: Glial scar formation is a reactive glial response confining injured regions in a central nervous system. However, it remains challenging to identify key factors formulating glial scar in response...
3.
Choi Y, Choi Y, Ko S, Cheon C, Kim T
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835418
Costunolide (CTL), an active compound isolated from Clarke and L, has been shown to induce apoptosis via reactive oxygen species (ROS) generation in various types of cancer cells. However, details...
4.
Kim T, Jeon S, Ko M, Du Y, Son S, Jang D, et al.
Antimicrob Agents Chemother
. 2022 Nov;
66(12):e0120122.
PMID: 36374087
Several plant-derived natural products with anti-SARS-CoV-2 activity have been evaluated for the potential to serve as chemotherapeutic agents for the treatment of COVID-19. Codonopsis lanceolata (CL) has long been used...
5.
Kim T, Kim J, Kwon H, Jeon S, Lee S, Jung H, et al.
Antiviral Res
. 2022 Oct;
208:105428.
PMID: 36252824
The continuous emergence of SARS-CoV-2 variants prolongs COVID-19 pandemic. Although SARS-CoV-2 vaccines and therapeutics are currently available, there is still a need for development of safe and effective drugs against...
6.
Won W, Choi H, Yoo J, Kim D, Kim T, Ju Y, et al.
Exp Mol Med
. 2022 Aug;
54(8):1188-1200.
PMID: 35982301
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation and the destruction of joints and systemic organs. RA is commonly accompanied by neuropsychiatric complications, such as cognitive impairment...
7.
Jang Y, Kim T, Jeon S, Lim H, Lee J, Kim S, et al.
Bioorg Chem
. 2022 Jul;
127:105985.
PMID: 35809512
We previously discovered that triterpenoid saponin platycodin D inhibits the SARS-CoV-2 entry to the host cell. Herein, we synthesized various saponin derivatives and established a structure-activity relationship of saponin-based antiviral...
8.
Jang M, Kim T, Sharma K, Kwon J, Yi E, Lee C
Exp Neurobiol
. 2021 Nov;
30(5):319-328.
PMID: 34737237
The TMEM43 has been studied in human diseases such as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5) and auditory neuropathy spectrum disorder (ANSD). In the heart, the p.(Ser358Leu) mutation has...
9.
Park M, Han A, Kim S, Kim T, Kim H, Lee C
J Enzyme Inhib Med Chem
. 2021 Sep;
36(1):2016-2024.
PMID: 34514924
Many studies have focussed on modulating the activity of γ-aminobutyric acid transaminase (GABA-T), a GABA-catabolizing enzyme, for treating neurological diseases, such as epilepsy and drug addiction. Nevertheless, human GABA-T synthesis...
10.
Jang M, Oh D, Yi E, Liu X, Ling J, Kim N, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(22).
PMID: 34050020
Genes that are primarily expressed in cochlear glia-like supporting cells (GLSs) have not been clearly associated with progressive deafness. Herein, we present a deafness locus mapped to chromosome 3p25.1 and...