Tae Hyung Won
Overview
Explore the profile of Tae Hyung Won including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
27
Citations
480
Followers
0
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Related Specialties
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Recent Articles
1.
Won T, Arifuzzaman M, Parkhurst C, Miranda I, Zhang B, Hu E, et al.
Nature
. 2025 Jan;
638(8049):216-224.
PMID: 39779854
Metabolites derived from the intestinal microbiota, including bile acids (BA), extensively modulate vertebrate physiology, including development, metabolism, immune responses and cognitive function. However, to what extent host responses balance the...
2.
Arifuzzaman M, Won T, Yano H, Uddin J, Emanuel E, Hu E, et al.
J Exp Med
. 2024 Mar;
221(5).
PMID: 38506708
Innate lymphoid cells (ILCs) can promote host defense, chronic inflammation, or tissue protection and are regulated by cytokines and neuropeptides. However, their regulation by diet and microbiota-derived signals remains unclear....
3.
Arifuzzaman M, Won T, Li T, Yano H, Digumarthi S, Heras A, et al.
Nature
. 2022 Nov;
611(7936):578-584.
PMID: 36323778
Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented short-chain fatty acid metabolites<sup>1,2</sup>, although the immunoregulatory roles of most fibre diets and their microbiota-derived metabolites remain poorly defined. Here,...
4.
Won T, Bok J, Nadig N, Venkatesh N, Nickles G, Greco C, et al.
Nat Commun
. 2022 Aug;
13(1):4828.
PMID: 35973982
The genomes of many filamentous fungi, such as Aspergillus spp., include diverse biosynthetic gene clusters of unknown function. We previously showed that low copper levels upregulate a gene cluster that...
5.
Kwon O, Ahn S, Jeon J, Park I, Won T, Sim C, et al.
Org Lett
. 2021 Jun;
23(12):4667-4671.
PMID: 34060857
Psammocindoles A-C (-), a new class of indole alkaloids, were isolated from a sponge. By combined spectroscopic analyses, the structures of these compounds were determined to be the indole-γ-lactams derived...
6.
Raffa N, Won T, Sukowaty A, Candor K, Cui C, Halder S, et al.
Proc Natl Acad Sci U S A
. 2021 Feb;
118(8).
PMID: 33593906
The maintenance of sufficient but nontoxic pools of metal micronutrients is accomplished through diverse homeostasis mechanisms in fungi. Siderophores play a well established role for iron homeostasis; however, no copper-binding...
7.
Bae J, Cho E, Park J, Won T, Seo S, Oh D, et al.
J Nat Prod
. 2020 Jan;
83(2):429-437.
PMID: 31967465
Isocadiolides A-H (-) and cadiolide N (), new polybrominated aromatic compounds, were isolated from a Korean sp. ascidian. On the basis of the results of extensive spectroscopic analyses, these compounds...
8.
Chu C, Murdock M, Jing D, Won T, Chung H, Kressel A, et al.
Nature
. 2019 Oct;
574(7779):543-548.
PMID: 31645720
Multicellular organisms have co-evolved with complex consortia of viruses, bacteria, fungi and parasites, collectively referred to as the microbiota. In mammals, changes in the composition of the microbiota can influence...
9.
Cho Y, Chung S, Kim H, Won T, Choi J, Kim I, et al.
J Control Release
. 2019 Jan;
296:241-249.
PMID: 30659905
The selective targeting of cytotoxic agents to a tumor has shown limited success by difficulties in identifying the appropriate target molecules, and more importantly, by the phenotypically dynamic nature of...
10.
Chung S, Cho Y, Choi J, Kim H, Won T, Kim S, et al.
Biomaterials
. 2018 Nov;
192:109-117.
PMID: 30447398
Despite the emergence of advanced therapeutics such as targeted therapy and immunotherapy in the modern oncology, cytotoxic chemotherapy still remains as the first-line treatment option in a wide range of...