David Artis
Overview
Explore the profile of David Artis including associated specialties, affiliations and a list of published articles.
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Articles
196
Citations
26131
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Recent Articles
1.
Neurath M, Artis D, Becker C
Lancet Gastroenterol Hepatol
. 2025 Mar;
PMID: 40086468
The intestinal barrier serves as a boundary between the mucosal immune system in the lamina propria and the external environment of the intestinal lumen, which contains a diverse array of...
2.
Feng X, Andersson T, Fluchter P, Gschwend J, Berest I, Muff J, et al.
Nat Immunol
. 2025 Mar;
PMID: 40074948
The tuft cell-group 2 innate lymphoid cell (ILC2) circuit orchestrates rapid type 2 responses upon detecting microbially derived succinate and luminal helminths. Our findings delineate key mechanistic steps involving IP3R2...
3.
Amisaki M, Zebboudj A, Yano H, Zhang S, Payne G, Chandra A, et al.
Nature
. 2025 Jan;
638(8052):1076-1084.
PMID: 39814891
Tertiary lymphoid structures (TLSs) are de novo ectopic lymphoid aggregates that regulate immunity in chronically inflamed tissues, including tumours. Although TLSs form due to inflammation-triggered activation of the lymphotoxin (LT)-LTβ...
4.
Won T, Arifuzzaman M, Parkhurst C, Miranda I, Zhang B, Hu E, et al.
Nature
. 2025 Jan;
638(8049):216-224.
PMID: 39779854
Metabolites derived from the intestinal microbiota, including bile acids (BA), extensively modulate vertebrate physiology, including development, metabolism, immune responses and cognitive function. However, to what extent host responses balance the...
5.
Mayassi T, Li C, Segerstolpe A, Brown E, Weisberg R, Nakata T, et al.
Nature
. 2024 Dec;
637(8044):E10.
PMID: 39643652
No abstract available.
6.
Troch K, Jakob M, Forster P, Jarick K, Schreiber J, Preusser A, et al.
Nat Commun
. 2024 Dec;
15(1):10566.
PMID: 39632879
Tissue-resident immune cells, such as innate lymphoid cells, mediate protective or detrimental immune responses at barrier surfaces. Upon activation by stromal or epithelial cell-derived alarmins, group 2 innate lymphoid cells...
7.
Liao Y, Gao I, Kusakabe T, Lin W, Grier A, Pan X, et al.
Nature
. 2024 Nov;
636(8043):697-704.
PMID: 39604728
The gut mycobiota is crucial for intestinal homeostasis and immune function. Yet its variability and inconsistent fungal colonization of laboratory mice hinders the study of the evolutionary and immune processes...
8.
9.
Mayassi T, Li C, Segerstolpe A, Brown E, Weisberg R, Nakata T, et al.
Nature
. 2024 Nov;
636(8042):447-456.
PMID: 39567686
The intestine is characterized by an environment in which host requirements for nutrient and water absorption are consequently paired with the requirements to establish tolerance to the outside environment. To...
10.
Hou X, Artis D
Curr Opin Gastroenterol
. 2024 Oct;
41(1):38-45.
PMID: 39417780
Purpose Of Review: Bidirectional regulation between neurons and immune cells in the intestine governs essential physiological processes, including digestion, metabolism and motility, while also controlling intestinal inflammation and maintaining tissue...