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Tae Hayashi

Explore the profile of Tae Hayashi including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 131
Followers 0
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Recent Articles
1.
Fukushima A, Hayashi T, Takeyoshi M
J Toxicol Sci . 2023 Sep; 48(9):507-511. PMID: 37661367
Allergic contact dermatitis is a common occupational and environmental health problem and setting of health-based exposure limits (HBELs) to prevent induction of skin sensitization is strongly desired. When manufacturing pharmaceuticals...
2.
Wang Y, Wang L, Seo N, Okumura S, Hayashi T, Akahori Y, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37446055
The benefits of CAR-T therapy could be expanded to the treatment of solid tumors through the use of derived autologous αβ T cell, but clinical trials of CAR-T therapy for...
3.
Fukushima A, Hayashi T, Takeyoshi M
J Appl Toxicol . 2022 May; 42(10):1723-1730. PMID: 35580980
Skin sensitization is an extremely important risk factor for occupational health and safety, and it would be desirable to set health-based exposure limits (HBELs) for the quantitative risk assessment (QRA)...
4.
Muraoka D, Seo N, Hayashi T, Tahara Y, Fujii K, Tawara I, et al.
J Clin Invest . 2019 Jan; 129(3):1278-1294. PMID: 30628894
Immune checkpoint inhibitors and adoptive transfer of gene-engineered T cells have emerged as novel therapeutic modalities for hard-to-treat solid tumors; however, many patients are refractory to these immunotherapies, and the...
5.
Ohtake T, Maeda Y, Hayashi T, Yamanaka H, Nakai M, Takeyoshi M
Toxicology . 2017 Nov; 393:9-14. PMID: 29100879
The skin sensitization potential of chemicals has been traditionally assessed using regulatory accepted in vivo methods, such as guinea pig maximization test or mouse local lymph node assays (LLNAs). A...
6.
Muraoka D, Seo N, Hayashi T, Hyuga-Amaike C, Okamori K, Tawara I, et al.
Oncotarget . 2017 Apr; 8(19):30766-30780. PMID: 28430604
Long-surviving memory CD8+ T cells generated by stimulation with appropriate tumor-associated antigens are the most aggressive and persistent tumoricidal effectors. In this event of memory CD8+ T cell development, the...
7.
Muraoka D, Harada N, Hayashi T, Tahara Y, Momose F, Sawada S, et al.
ACS Nano . 2014 Sep; 8(9):9209-18. PMID: 25180962
Because existing therapeutic cancer vaccines provide only a limited clinical benefit, a different vaccination strategy is necessary to improve vaccine efficacy. We developed a nanoparticulate cancer vaccine by encapsulating a...
8.
Miyazaki T, Ikeda Y, Kubo I, Suganuma S, Fujita N, Itakura M, et al.
Mamm Genome . 2014 Jul; 25(7-8):317-26. PMID: 24997020
Spontaneous testicular teratomas (STTs) composed by various kinds of tissues are derived from primordial germ cells (PGCs) in the fetal testes of the mouse. In contrast, intra-testicular grafts of the...