T R Sutter
Overview
Explore the profile of T R Sutter including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
1618
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Recent Articles
1.
DICK R, Kwak M, Sutter T, Kensler T
J Biol Chem
. 2001 Aug;
276(44):40803-10.
PMID: 11524419
There are several known routes for the metabolic detoxication of alpha,beta-unsaturated aldehydes and ketones, including conjugation to glutathione and reduction and oxidation of the aldehyde to an alcohol and a...
2.
Kwak M, Itoh K, Yamamoto M, Sutter T, Kensler T
Mol Med
. 2001 Jul;
7(2):135-45.
PMID: 11471548
Background: The induction of phase 2 enzymes by dithiolethiones such as oltipraz is an effective means for achieving protection against environmental carcinogens in animals and humans. Transcriptional control of the...
3.
Bofinger D, Feng L, Chi L, Love J, Stephen F, Sutter T, et al.
Toxicol Sci
. 2001 Jul;
62(2):299-314.
PMID: 11452143
Endometriosis is a debilitating disease estimated to affect 10% of reproductive-age women and characterized by the growth of endometrial tissue outside of the uterus. The present study characterizes a human...
4.
Guengerich F, Cai H, McMahon M, Hayes J, Sutter T, Groopman J, et al.
Chem Res Toxicol
. 2001 Jun;
14(6):727-37.
PMID: 11409944
Oxidation of the mycotoxin aflatoxin (AF) B1 yields the 8,9-epoxide, which nonenzymatically hydrolyzes rapidly to a dihydrodiol that in turn undergoes slow, base-catalyzed ring opening to a dialdehyde [Johnson, W....
5.
Hudson C, Schulte B, Sutter T, Norris J
Carcinogenesis
. 2001 Apr;
22(5):763-70.
PMID: 11323396
Syrian hamsters treated with estrogen and androgen for 8 months develop leiomyosarcomas in the vas deferens. Metabolism of estrogen by cytochrome P450s (CYPs) produces catechols and reactive oxygen species, and...
6.
Jefcoate C, Liehr J, Santen R, Sutter T, Yager J, Yue W, et al.
J Natl Cancer Inst Monogr
. 2000 Aug;
(27):95-112.
PMID: 10963622
Estrogen exposure represents the major known risk factor for development of breast cancer in women and is implicated in the development of prostate cancer in men. Human breast tissue has...
7.
Primiano T, Kensler T, Trush M, Sutter T
Adv Exp Med Biol
. 2000 Feb;
469:599-605.
PMID: 10667388
No abstract available.
8.
Starr T, Greenlee W, Neal R, Poland A, Sutter T
Environ Health Perspect
. 1999 Sep;
107(10):A492-3.
PMID: 10504157
Comments on Van den Berg, et al. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 106:775-792 (1998)
9.
Shimada T, Watanabe J, Kawajiri K, Sutter T, Guengerich F, Gillam E, et al.
Carcinogenesis
. 1999 Jul;
20(8):1607-13.
PMID: 10426814
Four polymorphic human cytochrome P450 (CYP) 1B1 allelic variants, namely Arg48,Ala119,Leu432,Asn453, Arg48,Ser119,Leu432,Asn453, Arg48, Ala119,Val432,Asn-453 and Arg48,Ser119,Val432,Asn453, were expressed in Escherichia coli together with human NADPH-P450 reductase and the recombinant proteins...
10.
Shimada T, Gillam E, Oda Y, Tsumura F, Sutter T, Guengerich F, et al.
Chem Res Toxicol
. 1999 Jul;
12(7):623-9.
PMID: 10409402
Recombinant human enzymes expressed in membranes obtained from Escherichia coli transformed with cytochrome P450 (P450) and NADPH-P450 reductase cDNAs were used to identify the human P450 enzymes that are most...