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T Nagate

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Articles 35
Citations 126
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Recent Articles
11.
Hirano T, Miyajima H, Nagate T, Hanada K, Hirose S, Okumura K, et al.
Cell Immunol . 1994 Feb; 153(2):277-86. PMID: 7907002
When B cells from BALB/c mice were cultured with lipopolysaccharide (LPS) and interleukin-4 (IL-4), a large amount of IgE was detected in the culture supernatants. The IgE production from unseparated...
12.
Inamoto Y, Ariyama S, Hamanaka Y, Okita K, Kaneta Y, Nagate T, et al.
J Clin Gastroenterol . 1993 Jan; 17 Suppl 1:S136-9. PMID: 8283008
Lipids from Helicobacter pylori were extracted, isolated by conventional DEAE-Sephadex and silica gel column chromatography, and then purified by preparative thin-layer chromatography. Simple and phospholipids were analyzed by HPTLC and...
13.
Omura S, Morimoto S, Nagate T, Adachi T, Kohno Y
Yakugaku Zasshi . 1992 Sep; 112(9):593-614. PMID: 1469609
A series of O-alkylated derivatives of erythromycin (EM) has been prepared and their biological properties were evaluated. Among them, clarithromycin (CAM, 6-O-methylerythromycin) exhibits most potent in vitro and in vivo...
14.
Yokoo C, Onodera A, Fukushima H, Numata K, Nagate T
J Antibiot (Tokyo) . 1992 Sep; 45(9):1533-9. PMID: 1429240
A series of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido] cephalosporins (1) having various substituted alkylthio groups at the C-3 position of the cephem nucleus were prepared and evaluated for antibacterial activity and oral...
15.
Yokoo C, Onodera A, Fukushima H, Numata K, Nagate T
J Antibiot (Tokyo) . 1992 Jun; 45(6):932-9. PMID: 1500361
A series of new 3-[(Z)-2-methoxycarbonylvinylthio]-7 beta-[(2- aminothiazol-4-yl)acetamido]-cephalosporins (1) having various oxyimino groups (Z-form) at the alpha position of the C-7 side chain was synthesized and evaluated for antibacterial activity and...
16.
Yokoo C, Goi M, Onodera A, Fukushima H, Nagate T
J Antibiot (Tokyo) . 1991 Dec; 44(12):1422-31. PMID: 1778793
A series of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(carboxymethoxyimino)ace tamido] cephalosporins (1) having various substituted-vinylthio groups at the C-3 position of the cephen nucleus was synthesized and evaluated for antibacterial activity and oral...
17.
Yokoo C, Goi M, Onodera A, Murata M, Nagate T, Watanabe Y
J Antibiot (Tokyo) . 1991 May; 44(5):498-506. PMID: 2061193
The synthesis, antibacterial activity and oral absorption in rats of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(carboxymethoxyimino)ace tamido] cephalosporins (1) having various substituted-alkylthio groups at the C-3 position of the cephem nucleus are described....
18.
Morimoto S, Adachi T, Misawa Y, Nagate T, Watanabe Y, Omura S
J Antibiot (Tokyo) . 1990 May; 43(5):544-9. PMID: 2358406
6-O-Methylerythromycin B has been synthesized from erythromycin B via regioselective methylation of the 6-hydroxyl group in 71% overall yield. This compound shows in vitro antibacterial activity comparable to erythromycins A...
19.
Morimoto S, Misawa Y, Adachi T, Nagate T, Watanabe Y, Omura S
J Antibiot (Tokyo) . 1990 Mar; 43(3):286-94. PMID: 2324013
A series of O-alkyl erythromycin A derivatives have been synthesized and their antibacterial activities compared with those of erythromycin A (1) and 6-O-methylerythromycin A (3). Methylation of the hydroxyl groups...
20.
Morimoto S, Nagate T, Sugita K, Ono T, Numata K, Miyachi J, et al.
J Antibiot (Tokyo) . 1990 Mar; 43(3):295-305. PMID: 2139023
The in vitro and in vivo antibacterial activities of 6-O-methylerythromycin A (TE-031, A-56268, or clarithromycin) and 6,11-di-O-methylerythromycin A (TE-032) have been compared with those of erythromycin A (EM) and josamycin...