T N Wells
Overview
Explore the profile of T N Wells including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
3899
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Recent Articles
1.
Schwarz M, Wells T, Proudfoot A
Recept Channels
. 2002 Mar;
7(6):417-28.
PMID: 11918345
To date, the available therapies for the treatment of HIV infection are targeted against proteins encoded by the virus itself. Thus, combination drug therapies for HIV with reverse transciptase and...
2.
Du X, Navdaev A, Clemetson J, Magnenat E, Wells T, Clemetson K
Thromb Haemost
. 2002 Jan;
86(5):1277-83.
PMID: 11816718
A new snake protein, named bilinexin, has been purified from Agkistrodon bilineatus venom by ion-exchange chromatography and gel filtration chromatography. Under non-reducing conditions it has a mass of 110 kDa...
3.
Klein A, Talvani A, Silva P, Martins M, Wells T, Proudfoot A, et al.
J Immunol
. 2001 Jun;
167(1):524-31.
PMID: 11418691
The understanding of the mechanisms underlying eosinophil recruitment in vivo may aid in the development of novel strategies for the treatment of allergic disorders. In this study, we investigated the...
4.
Stumbles P, Strickland D, Pimm C, Proksch S, Marsh A, McWilliam A, et al.
J Immunol
. 2001 Jun;
167(1):228-34.
PMID: 11418653
Dendritic cells (DC) were purified by flow cytometry from rat tracheal mucosa; they exhibited the phenotypic characteristics of immature DC including high endocytic activity, low CD80/86 expression, and in vitro...
5.
Elsner J, Dulkys Y, Kimmig D, Wells T, Proudfoot A, Kapp A
Int Arch Allergy Immunol
. 2001 Apr;
124(1-3):227-9.
PMID: 11306977
Eosinophils are predominant effector cells in allergic diseases attracted by several CC chemokines into the inflammatory tissue. According to their important role in attracting leukocytes, several kinds of chemokine receptor...
6.
Navdaev A, Clemetson J, Polgar J, Kehrel B, Glauner M, Magnenat E, et al.
J Biol Chem
. 2001 Apr;
276(24):20882-9.
PMID: 11287424
Aggretin, a potent platelet activator, was isolated from Calloselasma rhodostoma venom, and 30-amino acid N-terminal sequences of both subunits were determined. Aggretin belongs to the heterodimeric snake C-type lectin family...
7.
Proudfoot A, Power C, Wells T
Immunol Rev
. 2001 Jan;
177:246-56.
PMID: 11138781
One of the key characteristics of inflammation is the recruitment of leukocytes to the site of inflammation. Most anti-inflammatory strategies act intracellularly on the target cells, but after the cells...
8.
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity
Proudfoot A, Fritchley S, Borlat F, Shaw J, Vilbois F, Zwahlen C, et al.
J Biol Chem
. 2000 Dec;
276(14):10620-6.
PMID: 11116158
The chemokine RANTES (regulated on activation normal T cell expressed and secreted; CCL5) binds selectively to glycosaminoglycans (GAGs) such as heparin, chondroitin sulfate, and dermatan sulfate. The primary sequence of...
9.
Clemetson K, Clemetson J, Proudfoot A, Power C, Baggiolini M, Wells T
Blood
. 2000 Dec;
96(13):4046-54.
PMID: 11110672
Platelets are known to contain platelet factor 4 and beta-thromboglobulin, alpha-chemokines containing the CXC motif, but recent studies extended the range to the beta-family characterized by the CC motif, including...
10.