T N Johansen
Overview
Explore the profile of T N Johansen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
73
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Johansen T, Stensbol T, Nielsen B, Vogensen S, Frydenvang K, Slok F, et al.
Chirality
. 2001 Oct;
13(9):523-32.
PMID: 11579444
We have previously described (RS)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) as a potent agonist at the (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor subtype of (S)-glutamic acid (Glu) receptors. We now report the chromatographic resolution of...
2.
Bunch L, Johansen T, Brauner-Osborne H, Stensbol T, Johansen T, Krogsgaard-Larsen P, et al.
Bioorg Med Chem
. 2001 May;
9(4):875-9.
PMID: 11354670
Two hybrid analogues of the kainic acid receptor agonists, 2-amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)propionic acid (ATPA) and (2S,4R)-4-methylglutamic acid ((2S,4R)-4-Me-Glu), were designed, synthesized, and characterized in radioligand binding assays using cloned ionotropic and metabotropic...
3.
Madsen U, Brauner-Osborne H, Frydenvang K, Hvene L, Johansen T, Nielsen B, et al.
J Med Chem
. 2001 Apr;
44(7):1051-9.
PMID: 11297452
Using ibotenic acid (2) as a lead, two series of 3-isoxazolol amino acid ligands for (S)-glutamic acid (Glu, 1) receptors have been developed. Whereas analogues of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid [AMPA, (RS)-3]...
4.
Stensbol T, Jensen H, Nielsen B, Johansen T, Egebjerg J, Frydenvang K, et al.
Eur J Pharmacol
. 2001 Feb;
411(3):245-53.
PMID: 11164381
(RS)-2-Amino-3-(5-tert-butyl-3-hydroxy-4-isothiazolyl)propionic acid (thio-ATPA), a 3-isothiazolol analogue of (RS)-2-amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)propionic acid (ATPA), has previously been shown to be a relatively weak AMPA receptor agonist at native (S)-glutamic acid ((S)-Glu) receptors (EC(50)=14 microM),...
5.
Vogensen S, Jensen H, Stensbol T, Frydenvang K, Bang-Andersen B, Johansen T, et al.
Chirality
. 2000 Oct;
12(10):705-13.
PMID: 11054828
We have previously shown that (RS)-2-amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)isoxazol -4-yl] propionic acid (2-Me-Tet-AMPA) is a selective agonist at (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors, markedly more potent than AMPA itself, whereas the isomeric compound 1-Me-Tet-AMPA...
6.
Brauner-Osborne H, Hermit M, Nielsen B, Krogsgaard-Larsen P, Johansen T
Eur J Pharmacol
. 2000 Sep;
406(1):41-4.
PMID: 11011030
We have studied the pharmacological effects of (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) and the enantiomers of (RS)-2-amino-3-(3-hydroxy-1,2, 5-thiadiazol-4-yl)propionic acid (TDPA) on cloned human excitatory amino acid transporter subtypes 1, 2 and 3...
7.
Moller E, Egebjerg J, BREHM L, Stensbol T, Johansen T, Madsen U, et al.
Chirality
. 1999 Nov;
11(10):752-9.
PMID: 10561704
The phosphono amino acid, (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl+ ++]propio nic acid (ATPO), is a structural hybrid between the NMDA antagonist (RS)-2-amino-7-phosphonoheptanoic acid (AP7) and the AMPA and GluR5 agonist, (RS)-2-amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)propionic acid (ATPA). ATPO...
8.
Stensbol T, Borre L, Johansen T, Egebjerg J, Madsen U, Ebert B, et al.
Eur J Pharmacol
. 1999 Oct;
380(2-3):153-62.
PMID: 10513575
(RS)-2-Amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)propionic acid (ATPA), an analogue of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA). has previously been shown to be a relatively weak AMPA receptor agonist and a very potent agonist at the GluR5 subtype...
9.
Karla R, Ebert B, Thorkildsen C, Herdeis C, Johansen T, Nielsen B, et al.
J Med Chem
. 1999 Jun;
42(11):2053-9.
PMID: 10354414
(RS)-5-Amino-4-(4-chlorophenyl)pentanoic acid (10) and the R-form (11) and S-form (12) of (RS)-5-amino-3-(4-chlorophenyl)pentanoic acid, which are homologues of the 4-aminobutanoic acidB (GABAB) receptor agonist (RS)-4-amino-3-(4-chlorophenyl)butanoic acid (baclofen), were synthesized. Compound 10...
10.
Zegar I, Chary P, Jabil R, Tamura P, Johansen T, Lloyd R, et al.
Biochemistry
. 1998 Dec;
37(47):16516-28.
PMID: 9843418
The structure of the (-)-(7S,8R,9S,10R)-N6-[10-(7,8,9, 10-tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct at A7 of 5'-d(CGGACAAGAAG)-3'.5'-d(CTTCTTGTCCG)-3', derived from trans addition of the exocyclic N6-amino group of dA to (-)-(7S,8R,9R, 10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene [(-)-DE2], was determined using molecular...