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T Conrad Gilliam

Explore the profile of T Conrad Gilliam including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 4944
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Recent Articles
1.
Zhou X, Kurywchak P, Wolf-Dennen K, Che S, Sulakhe D, DSouza M, et al.
Mol Ther Methods Clin Dev . 2021 Sep; 22:360-376. PMID: 34514028
Bladder cancer (BC), a heterogeneous disease characterized by high recurrence rates, is diagnosed and monitored by cystoscopy. Accurate clinical staging based on biopsy remains a challenge, and additional, objective diagnostic...
2.
Sulakhe D, DSouza M, Wang S, Balasubramanian S, Athri P, Xie B, et al.
Brief Bioinform . 2018 Jun; 20(5):1754-1768. PMID: 29931155
In recent years, the emphasis of scientific inquiry has shifted from whole-genome analyses to an understanding of cellular responses specific to tissue, developmental stage or environmental conditions. One of the...
3.
Xie B, Laxman B, Hashemifar S, Stern R, Gilliam T, Maltsev N, et al.
PLoS One . 2018 Mar; 13(3):e0193334. PMID: 29534074
Basal airway epithelial cells (AEC) constitute stem/progenitor cells within the central airways and respond to mucosal injury in an ordered sequence of spreading, migration, proliferation, and differentiation to needed cell...
4.
Bainer R, Trendowski M, Cheng C, Pei D, Yang W, Paugh S, et al.
Cancer Manag Res . 2017 Oct; 9:397-410. PMID: 28979163
Gene signatures have been associated with outcome in pediatric acute lymphoblastic leukemia (ALL) and other malignancies. However, determining the molecular drivers of these expression changes remains challenging. In ALL blasts,...
5.
DSouza M, Sulakhe D, Wang S, Xie B, Hashemifar S, Taylor A, et al.
Methods Mol Biol . 2017 Aug; 1613:85-99. PMID: 28849559
Recent technological advances in genomics allow the production of biological data at unprecedented tera- and petabyte scales. Efficient mining of these vast and complex datasets for the needs of biomedical...
6.
Sulakhe D, Xie B, Taylor A, DSouza M, Balasubramanian S, Hashemifar S, et al.
Nucleic Acids Res . 2015 Nov; 44(D1):D882-7. PMID: 26590263
Lynx (http://lynx.ci.uchicago.edu) is a web-based database and a knowledge extraction engine. It supports annotation and analysis of high-throughput experimental data and generation of weighted hypotheses regarding genes and molecular mechanisms...
7.
Xie B, Agam G, Balasubramanian S, Xu J, Gilliam T, Maltsev N, et al.
J Comput Biol . 2015 Apr; 22(4):313-23. PMID: 25844670
Identifying high-confidence candidate genes that are causative for disease phenotypes, from the large lists of variations produced by high-throughput genomics, can be both time-consuming and costly. The development of novel...
8.
Dubchak I, Balasubramanian S, Wang S, Cem M, Meyden C, Sulakhe D, et al.
PLoS One . 2014 Dec; 9(12):e114903. PMID: 25506935
An essential step in the discovery of molecular mechanisms contributing to disease phenotypes and efficient experimental planning is the development of weighted hypotheses that estimate the functional effects of sequence...
9.
Sulakhe D, Taylor A, Balasubramanian S, Feng B, Xie B, Bornigen D, et al.
Nucleic Acids Res . 2014 Jun; 42(Web Server issue):W473-7. PMID: 24948611
Lynx is a web-based integrated systems biology platform that supports annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders...
10.
Maltsev N, Rzhetsky A, Gilliam T
Adv Exp Med Biol . 2014 Mar; 799:v - viii. PMID: 24678533
No abstract available.