T A Springer
Overview
Explore the profile of T A Springer including associated specialties, affiliations and a list of published articles.
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Articles
346
Citations
24325
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Recent Articles
11.
Shore R, Crocker D, Akcakaya H, Bennett R, Chapman P, Clook M, et al.
Ecotoxicology
. 2005 Dec;
14(8):877-93.
PMID: 16328715
In the European Union, first-tier assessment of the long-term risk to birds and mammals from pesticides is based on calculation of a deterministic long-term toxicity/exposure ratio (TER(lt)). The ratio is...
12.
Roelofs W, Crocker D, Shore R, Moore D, Smith G, Akcakaya H, et al.
Ecotoxicology
. 2005 Dec;
14(8):895-923.
PMID: 16328714
Long term exposure of skylarks to a fictitious insecticide and of wood mice to a fictitious fungicide were modelled probabilistically in a Monte Carlo simulation. Within the same simulation the...
13.
Bennett R, Dewhurst I, Fairbrother A, Hart A, Hooper M, Leopold A, et al.
Ecotoxicology
. 2005 Nov;
14(8):801-15.
PMID: 16292617
The long-term risks of pesticides to wildlife in the EU currently are assessed by comparing the lowest no-observed-effect concentration (NOEC) determined from the suite of endpoints measured in existing avian...
14.
Mancini E, Steen A, Rausina G, Wong D, Arnold W, Gostomski F, et al.
Environ Sci Technol
. 2002 Feb;
36(2):125-9.
PMID: 11831214
A public/private partnership was established in 1997, under the administrative oversight of the American Petroleum Institute (API), to develop aquatic toxicity data sufficient to calculate ambient water quality criteria for...
15.
de Chateau M, Chen S, Salas A, Springer T
Biochemistry
. 2001 Nov;
40(46):13972-9.
PMID: 11705388
We studied interactions in shear flow of cells bearing integrins alpha4beta1 or alpha4beta7 with VCAM-1 and MAdCAM-1 substrates in different divalent cations. Interestingly, Ca(2+) was essential for tethering in flow...
16.
Takagi J, Beglova N, Yalamanchili P, Blacklow S, Springer T
Proc Natl Acad Sci U S A
. 2001 Sep;
98(20):11175-80.
PMID: 11572973
Integrin beta subunits contain four cysteine-rich repeats in a long extracellular stalk that connects the headpiece to the membrane. Most mAbs to integrin activation epitopes map to these repeats, and...
17.
Manjunath N, Shankar P, Wan J, Weninger W, Crowley M, Hieshima K, et al.
J Clin Invest
. 2001 Sep;
108(6):871-8.
PMID: 11560956
The lineage relationship between short-lived effector T cells and long-lived memory cells is not fully understood. We have described T-GFP mice previously, in which naive and early activated T cells...
18.
Kamata T, Tieu K, Irie A, Springer T, Takada Y
J Biol Chem
. 2001 Sep;
276(47):44275-83.
PMID: 11557768
Several distinct regions of the integrin alpha(IIb) subunit have been implicated in ligand binding. To localize the ligand binding sites in alpha(IIb), we swapped all 27 predicted loops with the...
19.
Smith R, Fedyk E, Springer T, Mukaida N, Iglewski B, Phipps R
J Immunol
. 2001 Jun;
167(1):366-74.
PMID: 11418672
The destructive pulmonary inflammation associated with Pseudomonas aeruginosa colonization is caused, in part, by the production of the chemokine IL-8, which recruits neutrophils into the lung. The Pseudomonas autoinducer, N-3-oxododecanoyl...
20.
Jun C, Shimaoka M, Carman C, Takagi J, Springer T
Proc Natl Acad Sci U S A
. 2001 Jun;
98(12):6830-5.
PMID: 11391003
Dimeric intercellular adhesion molecule-1 (ICAM-1) binds more efficiently to lymphocyte function-associated antigen-1 (LFA-1) than monomeric ICAM-1. However, it is unknown whether dimerization enhances binding simply by providing two ligand-binding sites...