T A Springer
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Explore the profile of T A Springer including associated specialties, affiliations and a list of published articles.
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346
Citations
24325
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Recent Articles
1.
Samy K, Anderson D, Lo D, Mulvihill M, Song M, Farris A, et al.
Am J Transplant
. 2016 Nov;
17(5):1193-1203.
PMID: 27888551
Costimulation blockade (CoB) via belatacept is a lower-morbidity alternative to calcineurin inhibitor (CNI)-based immunosuppression. However, it has higher rates of early acute rejection. These early rejections are mediated in part...
2.
Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys H, Springer T, et al.
J Thromb Haemost
. 2015 Sep;
13(11):2063-75.
PMID: 26391536
Background: Recently, conformational activation of ADAMTS-13 was identified. This mechanism showed the evolution from a condensed conformation, in which the proximal MDTCS and distal T2-CUB2 domains are in close contact...
3.
Springer T
J Thromb Haemost
. 2011 Jul;
9 Suppl 1:130-43.
PMID: 21781248
Structural specialisations enable von Willebrand factor (VWF) to assemble during biosynthesis into helical tubules in Weibel-Palade bodies (WPB). Specialisations include a pH-regulated dimeric bouquet formed by the C-terminal half of...
4.
Springer T, Welch A
Appl Opt
. 2010 Aug;
32(4):517-25.
PMID: 20802719
A technique is described for the computer control of temperature during laser vessel welding. The technique is based on the use of thermal feedback from a calibrated IR sensor. The...
5.
Bonifacino J, DellAngelica E, Springer T
Curr Protoc Immunol
. 2008 Apr;
Chapter 8:Unit 8.3.
PMID: 18432858
Immunoprecipitation consists of multiple ordered steps: lysing the cell with detergent if the antigen (usually a protein) to be precipitated is membrane-bound; binding of a specific antigen to an antibody;...
6.
Bonifacino J, DellAngelica E, Springer T
Curr Protoc Protein Sci
. 2008 Apr;
Chapter 9:Unit 9.8.
PMID: 18429217
Immunoprecipitation is a technique in which an antigen is isolated by binding to a specific antibody attached to a sedimentable matrix. It is also used to analyze protein fractions separated...
7.
Springer T
Curr Protoc Protein Sci
. 2008 Apr;
Chapter 9:Unit 9.5.
PMID: 18429214
This unit describes the isolation of soluble or membrane-bound protein antigens from cells or homogenized tissue by immunoaffinity chromatography. This technique involves the elution of a single protein from an...
8.
Springer T
Curr Protoc Neurosci
. 2008 Apr;
Chapter 5:Unit 5.11.
PMID: 18428494
This technique involves elution of a single protein from an immunoaffinity column after prior elution of nonspecifically adsorbed proteins. Antibodies are coupled to Sepharose and the cell lysate is passed...
9.
Bonifacino J, DellAngelica E, Springer T
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 10:Unit 10.16.
PMID: 18265056
Immunoprecipitation is a technique in which an antigen is isolated by binding to a specific antibody attached to a sedimentable matrix. It is also used to analyze protein fractions separated...
10.
Springer T
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 10:Unit 10.11A.
PMID: 18265050
Immunoaffinity purification is a powerful technique for isolating proteins. Purifications of 10,000-fold or more can often be achieved in one step. This unit describes the isolation of soluble or membrane-bound...