Sylwia A Stopka
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Explore the profile of Sylwia A Stopka including associated specialties, affiliations and a list of published articles.
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47
Citations
573
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Recent Articles
1.
Venneti S, Kawakibi A, Ji S, Waszak S, Sweha S, Mota M, et al.
Cancer Discov
. 2025 Mar;
15(3):657.
PMID: 40025951
No abstract available.
2.
Rendo V, Lee E, Bossi C, Khuu N, Rudek M, Pal S, et al.
Sci Transl Med
. 2025 Feb;
17(786):eadn6274.
PMID: 39970230
Inhibitors of murine double minute homolog 2 (MDM2) represent a promising therapeutic approach for the treatment of wild-type glioblastomas (GBMs), reactivating p53 signaling to induce cancer cell death. We conducted...
3.
Schneider J, Kurmi K, Dai Y, Dhiman I, Joshi S, Gassaway B, et al.
Cell
. 2025 Feb;
188(5):1248-1264.e23.
PMID: 39919745
Little is known about metabolic vulnerabilities in oncogene-driven lung cancer. Here, we perform a phosphoproteomic screen in anaplastic lymphoma kinase (ALK)-rearranged ("ALK+") patient-derived cell lines and identify guanylate kinase 1...
4.
Vaidya K, Regan M, Lin J, Houle J, Gupta A, Stopka S, et al.
Angew Chem Int Ed Engl
. 2024 Dec;
64(5):e202420052.
PMID: 39714325
We report the development of a small molecule-based barcoding platform for pooled screening of nanoparticle delivery. Using aryl halide-based tags (halocodes), we achieve high-sensitivity detection via gas chromatography coupled with...
5.
Dragojevic S, Smith E, Regan M, Stopka S, Baquer G, Xue Z, et al.
Mol Cancer Ther
. 2024 Oct;
PMID: 39440433
Glioblastoma (GBM) remains one of the most therapy-resistant malignancies with frequent local failures despite aggressive surgery, chemotherapy, and ionizing radiation (IR). Small molecule inhibitors of DNA-dependent protein kinase (DNA-PKi's) are...
6.
Vaidya K, Regan M, Lin J, Houle J, Stopka S, Agar N, et al.
bioRxiv
. 2024 Oct;
PMID: 39386478
We report the development of a small molecule-based barcoding platform for pooled screening of nanoparticle delivery. Using aryl halide-based tags (halocodes), we achieve high-sensitivity detection via gas chromatography coupled with...
7.
Rendo V, Lee E, Bossi C, Khuu N, Rudek M, Pal S, et al.
medRxiv
. 2024 Aug;
PMID: 39211865
Statement Of Significance: Tissue sampling during this clinical trial allowed us to assess mechanisms of response and resistance associated with navtemadlin treatment in recurrent GBM. We report that clinically achievable...
8.
Rajakumar T, Hossain M, Stopka S, Micoogullari Y, Ang J, Agar N, et al.
Mol Biol Cell
. 2024 Jul;
35(9):ar117.
PMID: 39024283
The unfolded protein response (UPR) detects and mitigates the harmful effects of dysregulated endoplasmic reticulum (ER) function. The UPR has been best characterized as a protein quality control response, and...
9.
Hwang G, Pazyra-Murphy M, Seo H, Dhe-Paganon S, Stopka S, DiPiazza M, et al.
Cancer Res
. 2024 Mar;
84(6):872-886.
PMID: 38486486
Significance: Development of a benzarone derivative that inhibits EYA1 and impedes the growth of SHH medulloblastoma provides an avenue for improving treatment of this malignant pediatric brain cancer.
10.
Yu K, Basu S, Baquer G, Ahn R, Gantchev J, Jindal S, et al.
medRxiv
. 2024 Jan;
PMID: 38234840
One Sentence Summary: Integrative multi-omics analysis of stereotactic needle core biopsies in glioblastoma.