Sylvie Peraldi-Roux
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Explore the profile of Sylvie Peraldi-Roux including associated specialties, affiliations and a list of published articles.
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26
Citations
222
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Recent Articles
11.
Peraldi-Roux S
Methods Mol Biol
. 2012 Aug;
907:73-83.
PMID: 22907346
The construction of a large library of single-chain Fv (scFv) antibody fragments involves a random assortment of heavy and light chains. Although useful for the production of recombinant antibodies, this...
12.
Rebuffat S, Kammoun-Krichen M, Charfeddine I, Ayadi H, Bougacha-Elleuch N, Peraldi-Roux S
Immunobiology
. 2012 Aug;
218(3):285-91.
PMID: 22878044
Pro-inflammatory cytokines such as IL-1β and TNFα are known to affect thyroid function. They stimulate IL-6 secretion and modify epithelium integrity by altering junction proteins. To study the role of...
13.
Chentouf M, Dubois G, Jahannaut C, Castex F, Lajoix A, Gross R, et al.
PLoS One
. 2011 Aug;
6(8):e22954.
PMID: 21826222
Inappropriate food intake-related obesity and more importantly, visceral adiposity, are major risk factors for the onset of type 2 diabetes. Evidence is emerging that nutriment-induced β-cell dysfunction could be related...
14.
Belguith-Maalej S, Rebuffat S, Charfeddine I, Mnif M, Nadir R, Abid M, et al.
Immunobiology
. 2010 Nov;
216(5):571-8.
PMID: 21035230
Context: The PDS gene (SLC26A4) is responsible for Pendred syndrome (PS). Genetic analysis of PDS using Tunisian samples showed evidence for linkage and association with autoimmune thyroid diseases (AITD) emergence....
15.
Belguith-Maalej S, Hadj-Kacem H, Rebuffat S, Mnif-Feki M, Nguyen B, Abid M, et al.
Clin Lab
. 2010 Sep;
56(7-8):335-43.
PMID: 20857898
Background: We previously demonstrated that the PDS gene is involved in the genetic susceptibility to autoimmune thyroid diseases (AITD) in Tunisia. In the same population, we now investigated the presence...
16.
Rebuffat S, Nguyen B, Robert B, Castex F, Peraldi-Roux S
J Clin Endocrinol Metab
. 2007 Dec;
93(3):929-34.
PMID: 18073303
Context: Thyroid antibody-dependent cytotoxicity has been reported in autoimmune thyroid disease (AITD). Indeed, the role of thyroperoxidase (TPO) autoantibodies (aAbs) in complement-mediated damage by binding to TPO expressed on the...
17.
Kammoun-Krichen M, Bougacha-Elleuch N, Makni K, Rebai M, Peraldi-Roux S, Rebai A, et al.
Eur Cytokine Netw
. 2007 Oct;
18(4):196-200.
PMID: 17964974
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and autoimmune hypothyroidism (AH), are inherited as complex traits. Among the genes contributing to AITDs susceptibility are genes of the IL-1 family....
18.
Lajoix A, Badiou S, Peraldi-Roux S, Chardes T, Dietz S, Aknin C, et al.
Diabetes
. 2006 Nov;
55(12):3279-88.
PMID: 17130471
We previously showed that pancreatic beta-cells express neuronal nitric oxide synthase (nNOS) that controls insulin secretion through two catalytic activities: nitric oxide (NO) production and cytochrome c reductase activity. We...
19.
Rebuffat S, Bresson D, Nguyen B, Peraldi-Roux S
Int Immunol
. 2006 Jun;
18(7):1091-9.
PMID: 16735377
Auto-antibodies (aAbs) to thyroid peroxidase (TPO) interact with a restricted immunodominant region (IDR) divided into two overlapping regions A and B. Among the five major regions structuring the IDR/B, regions...
20.
Bresson D, Rebuffat S, Peraldi-Roux S
J Autoimmune Dis
. 2005 Mar;
2(1):2.
PMID: 15769293
Recent studies in the field of autoimmune thyroid diseases have largely focused on the delineation of B-cell auto-epitopes recognized by the main autoantigens to improve our understanding of how these...