Syed Murtuza Baker
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Explore the profile of Syed Murtuza Baker including associated specialties, affiliations and a list of published articles.
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21
Citations
295
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Recent Articles
1.
Preston R, Chrisp R, Dudek M, Morais M, Tian P, Williams E, et al.
Kidney Int
. 2024 Nov;
107(1):99-115.
PMID: 39515644
Kidney physiology shows diurnal variation, and a disrupted circadian rhythm is associated with kidney disease. However, it remains largely unknown whether glomeruli, the filtering units in the kidney, are under...
2.
Sheridan M, Maqbool M, Largeot A, Clayfield L, Xu J, Moncaut N, et al.
J Hematol Oncol
. 2024 Oct;
17(1):91.
PMID: 39380002
Background: The epigenetic factors KAT6A (MOZ/MYST3) and KMT2A (MLL/MLL1) interact in normal hematopoiesis to regulate progenitors' self-renewal. Both proteins are recurrently translocated in AML, leading to impairment of critical differentiation...
3.
Deshpande S, Georgaka S, Haley M, Sellers R, Minshull J, Nallala J, et al.
Bioinformatics
. 2024 Sep;
40(Suppl 2):ii174-ii181.
PMID: 39230703
Summary: Imagine if we could simultaneously predict spatial protein expression in tissues from their routine Hematoxylin and Eosin (H&E) stained images, and create tissue images given protein expression profiles thus...
4.
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
Dean I, Lee C, Tuong Z, Li Z, Tibbitt C, Willis C, et al.
Nat Commun
. 2024 Jan;
15(1):683.
PMID: 38267402
Immune cell dysfunction within the tumor microenvironment (TME) undermines the control of cancer progression. Established tumors contain phenotypically distinct, tumor-specific natural killer (NK) cells; however, the temporal dynamics, mechanistic underpinning...
5.
Menegatti S, Potts B, Paredes R, Garcia-Alegria E, Baker S, Kouskoff V
iScience
. 2023 Sep;
26(9):107583.
PMID: 37694151
During embryonic development, all blood progenitors are initially generated from endothelial cells that acquire a hemogenic potential. Blood progenitors emerge through an endothelial-to-hematopoietic transition regulated by the transcription factor RUNX1....
6.
Mannion A, Odell A, Baker S, Matthews L, Jones P, Cook G
Front Cell Dev Biol
. 2023 May;
11:1129015.
PMID: 37138793
CD146, also known as melanoma cell adhesion molecule (MCAM), is expressed in numerous cancers and has been implicated in the regulation of metastasis. We show that CD146 negatively regulates transendothelial...
7.
Finlay C, Parkinson J, Zhang L, Chan B, Ajendra J, Chenery A, et al.
Immunity
. 2023 Mar;
56(5):1064-1081.e10.
PMID: 36948193
The recent revolution in tissue-resident macrophage biology has resulted largely from murine studies performed in C57BL/6 mice. Here, using both C57BL/6 and BALB/c mice, we analyze immune cells in the...
8.
Li Z, Tuong Z, Dean I, Willis C, Gaspal F, Fiancette R, et al.
J Exp Med
. 2022 Apr;
219(6).
PMID: 35472220
Improving the efficacy of immune checkpoint therapies will require a better understanding of how immune cells are recruited and sustained in tumors. Here, we used the photoconversion of the tumor...
9.
Carrera S, ODonnell A, Li Y, Nowicki-Osuch K, Yang S, Baker S, et al.
Nucleic Acids Res
. 2021 Dec;
49(22):12744-12756.
PMID: 34850951
High levels of histone acetylation are associated with the regulatory elements of active genes, suggesting a link between acetylation and gene activation. We revisited this model, in the context of...
10.
Fiancette R, Finlay C, Willis C, Bevington S, Soley J, Ng S, et al.
Nat Immunol
. 2021 Sep;
22(10):1245-1255.
PMID: 34556884
Innate lymphoid cells (ILCs) are guardians of mucosal immunity, yet the transcriptional networks that support their function remain poorly understood. We used inducible combinatorial deletion of key transcription factors (TFs)...