Sybrin P Schroder
Overview
Explore the profile of Sybrin P Schroder including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
150
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Su Q, Louwerse M, Lammers R, Maurits E, Janssen M, Boot R, et al.
Chem Sci
. 2024 Sep;
PMID: 39246358
GBA2, the non-lysosomal β-glucosylceramidase, is an enzyme involved in glucosylceramide metabolism. Pharmacological inhibition of GBA2 by -alkyl iminosugars is well tolerated and benefits patients suffering from Sandhoff and Niemann-Pick type...
2.
Su Q, Schroder S, Lelieveld L, Ferraz M, Verhoek M, Boot R, et al.
Chembiochem
. 2023 Feb;
24(3):e202300728.
PMID: 36725348
No abstract available.
3.
de Boer C, Armstrong Z, Lit V, Barash U, Ruijgrok G, Boyango I, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(31):e2203167119.
PMID: 35881786
Heparan sulfate proteoglycans (HSPGs) mediate essential interactions throughout the extracellular matrix (ECM), providing signals that regulate cellular growth and development. Altered HSPG composition during tumorigenesis strongly aids cancer progression. Heparanase...
4.
de Boer C, McGregor N, Peterse E, Schroder S, Florea B, Jiang J, et al.
RSC Chem Biol
. 2022 Jan;
2(6):1701.
PMID: 34977585
[This corrects the article DOI: 10.1039/D0CB00045K.].
5.
Su Q, Schroder S, Lelieveld L, Ferraz M, Verhoek M, Boot R, et al.
Chembiochem
. 2021 Aug;
22(21):3090-3098.
PMID: 34459538
Glucocerebrosidase (GBA), a lysosomal retaining β-d-glucosidase, has recently been shown to hydrolyze β-d-xylosides and to transxylosylate cholesterol. Genetic defects in GBA cause the lysosomal storage disorder Gaucher disease (GD), and...
6.
de Boer C, McGregor N, Peterse E, Schroder S, Florea B, Jiang J, et al.
RSC Chem Biol
. 2021 Aug;
1(3):148-155.
PMID: 34458755
Cellulases and related β-1,4-glucanases are essential components of lignocellulose-degrading enzyme mixtures. The detection of β-1,4-glucanase activity typically relies on monitoring the breakdown of purified lignocellulose-derived substrates or synthetic chromogenic substrates,...
7.
Schroder S, Offen W, Males A, Jin Y, de Boer C, Enotarpi J, et al.
Chemistry
. 2021 Apr;
27(37):9519-9523.
PMID: 33878235
There is a vast genomic resource for enzymes active on carbohydrates. Lagging far behind, however, are functional chemical tools for the rapid characterization of carbohydrate-active enzymes. Activity-based probes (ABPs) offer...
8.
Ben Bdira F, Waudby C, Volkov A, Schroder S, Ab E, Codee J, et al.
Angew Chem Int Ed Engl
. 2020 Jun;
59(46):20508-20514.
PMID: 32533782
The single-domain GH11 glycosidase from Bacillus circulans (BCX) is involved in the degradation of hemicellulose, which is one of the most abundant renewable biomaterials in nature. We demonstrate that BCX...
9.
Artola M, Wouters S, Schroder S, de Boer C, Chen Y, Petracca R, et al.
European J Org Chem
. 2019 Dec;
2019(6):1397-1404.
PMID: 31787842
Cyclophellitol aziridine and its configurational and functional isomers are powerful covalent inhibitors of retaining glycosidases, and find application in fundamental studies on glycosidases, amongst others in relation to inherited lysosomal...
10.
Wu L, Armstrong Z, Schroder S, de Boer C, Artola M, Aerts J, et al.
Curr Opin Chem Biol
. 2019 Aug;
53:25-36.
PMID: 31419756
As the scope of modern genomics technologies increases, so does the need for informative chemical tools to study functional biology. Activity-based probes (ABPs) provide a powerful suite of reagents to...