Syandan Chakraborty
Overview
Explore the profile of Syandan Chakraborty including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
655
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Phillipou A, Lay C, Carver C, Messenger C, Evans J, Lewis A, et al.
SLAS Discov
. 2019 Dec;
25(2):163-175.
PMID: 31875412
Malfunctions in the basic epigenetic mechanisms such as histone modifications, DNA methylation, and chromatin remodeling are implicated in a number of cancers and immunological and neurodegenerative conditions. Within GlaxoSmithKline (GSK)...
2.
Lao Y, Li M, Gao M, Shao D, Chi C, Huang D, et al.
Adv Sci (Weinh)
. 2018 Jul;
5(7):1700540.
PMID: 30027026
CRISPR/Cas9 technology enables targeted gene editing; yet, the efficiency and specificity remain unsatisfactory, particularly for the nonvirally delivered, plasmid-based CRISPR/Cas9 system. To tackle this, a self-assembled micelle is developed and...
3.
Wang H, Song Z, Lao Y, Xu X, Gong J, Cheng D, et al.
Proc Natl Acad Sci U S A
. 2018 Apr;
115(19):4903-4908.
PMID: 29686087
Effective and safe delivery of the CRISPR/Cas9 gene-editing elements remains a challenge. Here we report the development of PEGylated nanoparticles (named P-HNPs) based on the cationic α-helical polypeptide poly(γ-4-((2-(piperidin-1-yl)ethyl)aminomethyl)benzyl-l-glutamate) for...
4.
Charoensook S, Williams D, Chakraborty S, Leong K, Vunjak-Novakovic G
Integr Biol (Camb)
. 2017 Nov;
9(12):956-967.
PMID: 29168874
In vitro models of the neuromuscular junction (NMJ) are emerging as a valuable tool to study synaptogenesis, synaptic maintenance, and pathogenesis of neurodegenerative diseases. Many models have previously been developed...
5.
Wang H, Li M, Lee C, Chakraborty S, Kim H, Bao G, et al.
Chem Rev
. 2017 Jun;
117(15):9874-9906.
PMID: 28640612
Genome editing offers promising solutions to genetic disorders by editing DNA sequences or modulating gene expression. The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 (CRISPR/Cas9) technology can be...
6.
Christoforou N, Chakraborty S, Kirkton R, Adler A, Addis R, Leong K
Sci Rep
. 2017 Jan;
7:40285.
PMID: 28071742
Transdifferentiation has been described as a novel method for converting human fibroblasts into induced cardiomyocyte-like cells. Such an approach can produce differentiated cells to study physiology or pathophysiology, examine drug...
7.
Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey G, et al.
Biomaterials
. 2016 Feb;
85:180-194.
PMID: 26874281
Access to smooth muscle cells (SMC) would create opportunities for tissue engineering, drug testing, and disease modeling. Herein we report the direct conversion of human endothelial progenitor cells (EPC) to...
8.
Lorden E, Miller K, Ibrahim M, Bashirov L, Hammett E, Chakraborty S, et al.
Acta Biomater
. 2015 Dec;
32:100-109.
PMID: 26708709
Statement Of Significance: In severe burns treated with skin grafting, between 30% and 90% of patients develop hypertrophic scars (HSc). There are no therapies to prevent HSc, and treatments are...
9.
Chakraborty S, Ji H, Chen J, Gersbach C, Leong K
Sci Rep
. 2014 Dec;
4:7403.
PMID: 25492703
Transgene insertion plays an important role in gene therapy and in biological studies. Transposon-based systems that integrate transgenes by transposase-catalyzed "cut-and-paste" mechanism have emerged as an attractive system for transgenesis....
10.
Chakraborty S, Ji H, Kabadi A, Gersbach C, Christoforou N, Leong K
Stem Cell Reports
. 2014 Dec;
3(6):940-7.
PMID: 25448066
Gene activation by the CRISPR/Cas9 system has the potential to enable new approaches to science and medicine, but the technology must be enhanced to robustly control cell behavior. We show...