Swatilekha Ghosh
Overview
Explore the profile of Swatilekha Ghosh including associated specialties, affiliations and a list of published articles.
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21
Citations
288
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Recent Articles
11.
Chakraborty S, Ghosh S, Banerjee B, Santra A, Bhat J, Adhikary A, et al.
Apoptosis
. 2016 Jul;
21(10):1106-24.
PMID: 27392939
The efficacy of cancer chemotherapeutics is limited by side effects resulting from narrow therapeutic windows between the anticancer activity of a drug and its cytotoxicity. Thus identification of small molecules...
12.
Chakraborty S, Ghosh S, Banerjee B, Santra A, Adhikary A, Misra A, et al.
Front Pharmacol
. 2016 May;
7:114.
PMID: 27199756
Triple-negative breast cancer (TNBC), is a specific subtype of epithelial breast tumors that are immuno-histochemically negative for the protein expression of the estrogen receptor (ER), the progesterone receptor (PR) and...
13.
Ahir M, Bhattacharya S, Karmakar S, Mukhopadhyay A, Mukherjee S, Ghosh S, et al.
Biomaterials
. 2015 Nov;
76:115-32.
PMID: 26520043
Metal oxide nanoparticles are the forthcoming anti-tumor therapeutics and provide a versatile platform in the development of therapeutic approaches for drug-resistant cancers such as triple negative breast cancer (TNBC). Copper...
14.
Bhattacharya S, Ahir M, Patra P, Mukherjee S, Ghosh S, Mazumdar M, et al.
Biomaterials
. 2015 Mar;
51:91-107.
PMID: 25771001
Thymoquinone (TQ), a major active constituent of black seeds of Nigella sativa, has potential medical applications including spectrum of therapeutic properties against different cancers. However, little is known about their...
15.
Ghosh S, Adhikary A, Chakraborty S, Bhattacharjee P, Mazumder M, Putatunda S, et al.
J Biol Chem
. 2014 Dec;
290(7):3936-49.
PMID: 25527500
Triple negative breast cancers (TNBC) are among the most aggressive and therapy-resistant breast tumors and currently possess almost no molecular targets for therapeutic options in this horizon. In the present...
16.
Adhikary A, Chakraborty S, Mazumdar M, Ghosh S, Mukherjee S, Manna A, et al.
J Biol Chem
. 2014 Aug;
289(37):25431-44.
PMID: 25086032
The evolution of the cancer cell into a metastatic entity is the major cause of death in patients with cancer. It has been acknowledged that aberrant activation of a latent...
17.
Ghosh S, Adhikary A, Chakraborty S, Nandi P, Mohanty S, Chakraborty S, et al.
J Biol Chem
. 2012 Aug;
287(39):32881-96.
PMID: 22851172
Multiple mechanisms have been proposed by which tumors induce T cell apoptosis to circumvent tumor immune-surveillance. Although sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) have long been known to regulate intracellular Ca(2+) homeostasis,...
18.
Putatunda S, Chakraborty S, Ghosh S, Nandi P, Chakraborty S, Sen P, et al.
Eur J Med Chem
. 2012 Jun;
54:223-31.
PMID: 22658336
A regioselective N1-alkylation of 3,4-dihydropyrimidin-2(1H)-ones using a very efficient mild base Cs(2)CO(3) and alkyl halides at room temperature has been reported. The selectivity of this methodology is excellent and the...
19.
Nandi P, Ghosh S, Jana K, Sen P
PLoS One
. 2012 Feb;
7(1):e30552.
PMID: 22291985
Mammalian sperm capacitation is an essential prerequisite to fertilization. Although progress is being made in understanding the physiology and biochemistry of capacitation, little has been yet explored about the potential...
20.
Mukherjee C, Ghosh S, Nandi P, Sen P, Misra A
Eur J Med Chem
. 2010 Oct;
45(12):6012-9.
PMID: 20952103
Synthesis of a series of novel (6-deoxy-glycopyranosid-6-yl) sulfone derivatives has been achieved using a general synthetic strategy. Yields were excellent in every case. The synthetic compounds were evaluated for their...