Efficient Synthesis of (6-deoxy-glycopyranosid-6-yl) Sulfone Derivatives and Their Effect on Ca2+-ATPase
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Abstract
Synthesis of a series of novel (6-deoxy-glycopyranosid-6-yl) sulfone derivatives has been achieved using a general synthetic strategy. Yields were excellent in every case. The synthetic compounds were evaluated for their biological potential against Ca2+-ATPase, an important enzyme involves in transporting Ca2+ across the cell membranes.
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Bioisosteres of Carbohydrate Functional Groups in Glycomimetic Design.
Hevey R Biomimetics (Basel). 2019; 4(3).
PMID: 31357673 PMC: 6784292. DOI: 10.3390/biomimetics4030053.