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Swapnil K Sonkusare

Explore the profile of Swapnil K Sonkusare including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 1348
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Recent Articles
1.
Strobel R, Ta H, Young A, Wisniewski A, Norman A, Rotar E, et al.
J Thorac Cardiovasc Surg . 2024 Apr; 168(4):e121-e132. PMID: 38678474
Objective: Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel important in many physiological and pathophysiological processes, including pulmonary disease. Using a murine model, we previously demonstrated that...
2.
Ta H, Kuppusamy M, Sonkusare S, Roeser M, Laubach V
Respir Res . 2024 Apr; 25(1):172. PMID: 38637760
The success of lung transplantation is limited by the high rate of primary graft dysfunction due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory response, lung...
3.
Wolpe A, Luse M, Baryiames C, Schug W, Wolpe J, Johnstone S, et al.
Sci Signal . 2024 Jan; 17(821):eadg2622. PMID: 38289985
Targeted degradation regulates the activity of the transcriptional repressor Bcl6 and its ability to suppress oxidative stress and inflammation. Here, we report that abundance of endothelial Bcl6 is determined by...
4.
Kuppusamy M, Ta H, Davenport H, Bazaz A, Kulshrestha A, Daneva Z, et al.
Sci Signal . 2023 Oct; 16(808):eadg1553. PMID: 37874885
Lung ischemia-reperfusion injury (IRI), characterized by inflammation, vascular permeability, and lung edema, is the major cause of primary graft dysfunction after lung transplantation. Here, we investigated the cellular mechanisms underlying...
5.
Villalba N, Sackheim A, Lawson M, Haines L, Chen Y, Sonkusare S, et al.
J Immunol . 2023 Jul; 211(4):648-657. PMID: 37405700
Drugs are needed to protect against the neutrophil-derived histones responsible for endothelial injury in acute inflammatory conditions such as trauma and sepsis. Heparin and other polyanions can neutralize histones but...
6.
Kuppusamy M, Ta H, Davenport H, Bazaz A, Kulshrestha A, Daneva Z, et al.
bioRxiv . 2023 Jul; PMID: 37397979
Lung ischemia-reperfusion injury (IRI), characterized by inflammation, vascular permeability, and lung edema, is the major cause of primary graft dysfunction after lung transplantation. We recently reported that endothelial cell (EC)...
7.
Dietrich A, Behringer E, Taylor M, Sonkusare S
Front Mol Biosci . 2023 May; 10:1201614. PMID: 37187892
No abstract available.
8.
Wong D, Auguste G, Lino Cardenas C, Turner A, Chen Y, Song Y, et al.
Circ Res . 2023 Apr; 132(9):1144-1161. PMID: 37017084
Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic insights for...
9.
Ruddiman C, Peckham R, Luse M, Chen Y, Kuppusamy M, Corliss B, et al.
JCI Insight . 2023 Apr; 8(9). PMID: 37014698
Lipid regulation of ion channels is largely explored using in silico modeling with minimal experimentation in intact tissue; thus, the functional consequences of these predicted lipid-channel interactions within native cellular...
10.
Daneva Z, Chen Y, Ta H, Manchikalapudi V, Bazaz A, Laubach V, et al.
Pulm Circ . 2023 Jan; 13(1):e12186. PMID: 36686408
Endothelial cells (ECs) from small pulmonary arteries (PAs) release nitric oxide (NO) and prostacyclin, which lower pulmonary arterial pressure (PAP). In pulmonary hypertension (PH), the levels of endothelium-derived NO and...