Eric L Cope
Overview
Explore the profile of Eric L Cope including associated specialties, affiliations and a list of published articles.
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5
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160
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Recent Articles
1.
Ottolini M, Daneva Z, Chen Y, Cope E, Kasetti R, Zode G, et al.
J Physiol
. 2020 May;
598(17):3577-3596.
PMID: 32463112
Key Points: Endothelial cell TRPV4 (TRPV4 ) channels exert a dilatory effect on the resting diameter of resistance mesenteric and pulmonary arteries. Functional intermediate- and small-conductance K (IK and SK)...
2.
Ottolini M, Hong K, Cope E, Daneva Z, DeLalio L, Sokolowski J, et al.
Circulation
. 2020 Feb;
141(16):1318-1333.
PMID: 32008372
Background: Impaired endothelium-dependent vasodilation is a hallmark of obesity-induced hypertension. The recognition that Ca signaling in endothelial cells promotes vasodilation has led to the hypothesis that endothelial Ca signaling is...
3.
Artamonov M, Sonkusare S, Good M, Momotani K, Eto M, Isakson B, et al.
Sci Signal
. 2018 Nov;
11(554).
PMID: 30377223
Smooth muscle contraction is triggered when Ca/calmodulin-dependent myosin light chain kinase (MLCK) phosphorylates the regulatory light chain of myosin (RLC). However, blood vessels from -deficient mouse embryos retain the ability...
4.
Hong K, Cope E, DeLalio L, Marziano C, Isakson B, Sonkusare S
Arterioscler Thromb Vasc Biol
. 2018 Jan;
38(3):542-554.
PMID: 29301784
Objective: Several physiological stimuli activate smooth muscle cell (SMC) GPCRs (G protein-coupled receptors) to cause vasoconstriction. As a protective mechanism against excessive vasoconstriction, SMC GPCR stimulation invokes endothelial cell vasodilatory...
5.
Marziano C, Hong K, Cope E, Kotlikoff M, Isakson B, Sonkusare S
J Am Heart Assoc
. 2017 Dec;
6(12).
PMID: 29275372
Background: Recent studies demonstrate that spatially restricted, local Ca signals are key regulators of endothelium-dependent vasodilation in systemic circulation. There are drastic functional differences between pulmonary arteries (PAs) and systemic...