Suzanne van Sommeren
Overview
Explore the profile of Suzanne van Sommeren including associated specialties, affiliations and a list of published articles.
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12
Citations
2127
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Recent Articles
1.
Visschedijk M, Spekhorst L, Cheng S, van Loo E, Jansen B, Blokzijl T, et al.
J Crohns Colitis
. 2018 Jan;
12(5):582-588.
PMID: 29361163
Background And Aims: Crohn's disease [CD] is a chronic inflammatory disease with unpredictable behaviour. More than half of CD patients eventually develop complications such as stenosis, for which they then...
2.
Huang H, Fang M, Jostins L, Mirkov M, Boucher G, Anderson C, et al.
Nature
. 2017 Jun;
547(7662):173-178.
PMID: 28658209
Inflammatory bowel diseases are chronic gastrointestinal inflammatory disorders that affect millions of people worldwide. Genome-wide association studies have identified 200 inflammatory bowel disease-associated loci, but few have been conclusively resolved...
3.
Liu J, van Sommeren S, Huang H, Ng S, Alberts R, Takahashi A, et al.
Nat Genet
. 2015 Jul;
47(9):979-986.
PMID: 26192919
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease (IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or Immunochip genotype...
4.
Knights D, Silverberg M, Weersma R, Gevers D, Dijkstra G, Huang H, et al.
Genome Med
. 2015 Jan;
6(12):107.
PMID: 25587358
Background: Human genetics and host-associated microbial communities have been associated independently with a wide range of chronic diseases. One of the strongest associations in each case is inflammatory bowel disease...
5.
Juyal G, Negi S, Sood A, Gupta A, Prasad P, Senapati S, et al.
Gut
. 2014 May;
64(4):571-9.
PMID: 24837172
Objective: Over 100 ulcerative colitis (UC) loci have been identified by genome-wide association studies (GWASs) primarily in Caucasians (CEUs). Many of them have weak effects on disease susceptibility, and the...
6.
van Sommeren S, Janse M, Karjalainen J, Fehrmann R, Franke L, Fu J, et al.
Inflamm Bowel Dis
. 2014 Apr;
20(6):987-94.
PMID: 24739630
Background: The clinical presentation of the inflammatory bowel diseases (IBD) is extremely heterogenous and is characterized by various extraintestinal manifestations and complications (EIM). Increasing genetic insight for IBD and EIM...
7.
Li H, Chan L, Bartuzi P, Melton S, Weber A, Ben-Shlomo S, et al.
Gastroenterology
. 2014 Apr;
147(1):184-195.e3.
PMID: 24727021
Background & Aims: Activation of the transcription factor nuclear factor-κB (NF-κB) has been associated with the development of inflammatory bowel disease (IBD). Copper metabolism MURR1 domain containing 1 (COMMD1), a...
8.
Fransen K, van Sommeren S, Westra H, Veenstra M, Lamberts L, Modderman R, et al.
Inflamm Bowel Dis
. 2014 Mar;
20(5):777-82.
PMID: 24662057
Background: The Th17/IL23 pathway has both genetically and biologically been implicated in the pathogenesis of the inflammatory bowel diseases (IBD), Crohn's disease, and ulcerative colitis. So far, it is unknown...
9.
Smeekens S, Ng A, Kumar V, Johnson M, Plantinga T, van Diemen C, et al.
Nat Commun
. 2013 Jan;
4:1342.
PMID: 23299892
Candida albicans is the most common human fungal pathogen causing mucosal and systemic infections. However, human antifungal immunity remains poorly defined. Here by integrating transcriptional analysis and functional genomics, we...
10.
van Sommeren S, Visschedijk M, Festen E, de Jong D, Ponsioen C, Wijmenga C, et al.
Inflamm Bowel Dis
. 2011 Jul;
17(8):1714-8.
PMID: 21744425
Background: Inflammatory bowel diseases (IBDs), consisting of ulcerative colitis (UC) and Crohn's disease (CD), are complex disorders with multiple genes contributing to disease pathogenesis. A recent genome-wide association scan identified...