Cisca Wijmenga
Overview
Explore the profile of Cisca Wijmenga including associated specialties, affiliations and a list of published articles.
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479
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50322
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Recent Articles
1.
Demirkan A, Dongen J, Finnicum C, Westra H, Jankipersadsing S, Willemsen G, et al.
BMC Genomics
. 2024 Dec;
25(1):1224.
PMID: 39702006
Microbiome influences multiple human systems, but its effects on gene methylation is unknown. We investigated the relations between gene methylation in blood and the abundance of common gut bacteria profiled...
2.
Simpson H, Smits E, Moerkens R, Wijmenga C, Mooiweer J, Jonkers I, et al.
Trends Mol Med
. 2024 Oct;
31(2):117-137.
PMID: 39448329
Coeliac disease (CeD) is an immune-mediated disorder characterised by gluten-triggered inflammation and damage in the small intestine, with lifelong gluten-free diet (GFD) as the only treatment. It is a multifactorial...
3.
Tan I, Modderman R, Stachurska A, Almeida R, de Vries R, Heersema D, et al.
Brain Commun
. 2024 Jul;
6(4):fcae209.
PMID: 38978729
Multiple sclerosis is a chronic demyelinating disease of the central nervous system. There is a need for new circulating biomarkers for multiple sclerosis, in particular, markers that differentiate multiple sclerosis...
4.
Moerkens R, Mooiweer J, Ramirez-Sanchez A, Oelen R, Franke L, Wijmenga C, et al.
Cell Rep
. 2024 Jun;
43(7):114247.
PMID: 38907996
Human induced pluripotent stem cell (hiPSC)-derived intestinal organoids are valuable tools for researching developmental biology and personalized therapies, but their closed topology and relative immature state limit applications. Here, we...
5.
Lincoln M, Connally N, Axisa P, Gasperi C, Mitrovic M, van Heel D, et al.
Nat Genet
. 2024 May;
56(5):838-845.
PMID: 38741015
Autoimmune and inflammatory diseases are polygenic disorders of the immune system. Many genomic loci harbor risk alleles for several diseases, but the limited resolution of genetic mapping prevents determining whether...
6.
Garmaeva S, Sinha T, Gulyaeva A, Kuzub N, Spreckels J, Andreu-Sanchez S, et al.
Nat Commun
. 2024 Mar;
15(1):1945.
PMID: 38431663
Early development of the gut ecosystem is crucial for lifelong health. While infant gut bacterial communities have been studied extensively, the infant gut virome remains under-explored. To study the development...
7.
Fernandez-Pato A, Sinha T, Gacesa R, Andreu-Sanchez S, Gois M, Gelderloos-Arends J, et al.
Sci Rep
. 2024 Feb;
14(1):3911.
PMID: 38366085
The lack of standardization in the methods of DNA extraction from fecal samples represents the major source of experimental variation in the microbiome research field. In this study, we aimed...
8.
Zhernakova D, Wang D, Liu L, Andreu-Sanchez S, Zhang Y, Ruiz-Moreno A, et al.
Nature
. 2024 Jan;
625(7996):813-821.
PMID: 38172637
Although the impact of host genetics on gut microbial diversity and the abundance of specific taxa is well established, little is known about how host genetics regulates the genetic diversity...
9.
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity
Eckold C, van Doorn C, Ruslami R, Ronacher K, Riza A, van Veen S, et al.
Clin Transl Med
. 2023 Aug;
13(9):e1375.
PMID: 37649224
Background: People with diabetes are more likely to develop tuberculosis (TB) and to have poor TB-treatment outcomes than those without. We previously showed that blood transcriptomes in people with TB-diabetes...
10.
Gois M, Fernandez-Pato A, Huss A, Gacesa R, Wijmenga C, Weersma R, et al.
Front Microbiol
. 2023 Aug;
14:1223120.
PMID: 37637104
The rising use of pesticides in modern agriculture has led to a shift in disease burden in which exposure to these chemicals plays an increasingly important role. The human gut...