Suzanne C Crawley
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Explore the profile of Suzanne C Crawley including associated specialties, affiliations and a list of published articles.
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13
Citations
440
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Recent Articles
1.
Paavola K, Roda J, Lin V, Chen P, OHollaren K, Ventura R, et al.
Cancer Immunol Res
. 2021 Aug;
9(11):1283-1297.
PMID: 34426457
Suppressive myeloid cells inhibit antitumor immunity by preventing T-cell responses. Immunoglobulin-like transcript 3 (ILT3; also known as LILRB4) is highly expressed on tumor-associated myeloid cells and promotes their suppressive phenotype....
2.
Lyman S, Crawley S, Gong R, Adamkewicz J, McGrath G, Chew J, et al.
PLoS One
. 2011 Mar;
6(3):e17692.
PMID: 21408192
Background: Many proteins that are dysregulated or mutated in cancer cells rely on the molecular chaperone HSP90 for their proper folding and activity, which has led to considerable interest in...
3.
Kwon S, Munroe X, Crawley S, Lee H, Spong S, Bradham D, et al.
Int J Oncol
. 2007 Sep;
31(4):693-703.
PMID: 17786299
Connective tissue growth factor (CTGF/CCN2) is thought to play a role in normal wound repair and bone remodeling, but also promotes fibrosis in several disease processes including diabetic nephropathy, sclerodoma...
4.
Park E, Oh H, Gum Jr J, Crawley S, Kakar S, Engel J, et al.
Clin Cancer Res
. 2006 Sep;
12(18):5403-10.
PMID: 17000673
Purpose: Mucinous cancers and signet ring carcinomas are distinct classes of colon cancers characterized by their production of copious quantities of intestinal goblet cell mucin, MUC2. Deletion of transcription factor...
5.
Hokari R, Lee H, Crawley S, Yang S, Gum Jr J, Miura S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2005 Oct;
289(5):G949-59.
PMID: 16227528
VIP exerts a spectrum of effects as a potent anti-inflammatory factor. In addition, VIP increases expression of MUC2, a major intestinal secretory mucin. We therefore investigated the effects of VIP...
6.
Ahn D, Crawley S, Hokari R, Kato S, Yang S, Li J, et al.
Cell Physiol Biochem
. 2005 Jan;
15(1-4):29-40.
PMID: 15665513
The molecular mechanisms responsible for TNF-alpha-mediated MUC2 intestinal mucin up-regulation in HM3 colon adenocarcinoma cells were analyzed using promoter-reporter assays of the 5'-flanking region of the MUC2 gene. Chemical inhibitors,...
7.
Gum Jr J, Hicks J, Crawley S, Yang S, Borowsky A, Dahl C, et al.
Mol Cancer Res
. 2004 Sep;
2(9):504-13.
PMID: 15383629
The colonic epithelium contains three major types of mature cells, namely, absorptive, goblet, and enteroendocrine cells. These cells are maintained by a complex process of cell renewal involving progenitor and...
8.
Gum Jr J, Hicks J, Crawley S, Dahl C, Yang S, Roberton A, et al.
J Biol Chem
. 2003 Sep;
278(49):49600-9.
PMID: 12958310
Human intestinal mucin genes MUC3A and MUC3B are members of a membrane mucin gene family residing at chromosome 7q22. In this paper, we utilized genomic and cDNA cloning to elucidate...
9.
Ho J, Jaituni R, Crawley S, Yang S, Gum J, Kim Y
Int J Oncol
. 2003 Jul;
23(3):585-92.
PMID: 12888891
The nucleic acid sequence of the human gene, MUC17, indicates that this mucin contains an SEA domain, a transmembrane domain, and putative N-glycosylation sites in the carboxyl terminus. Mucins that...
10.
Park H, Kim J, Kim G, Bae H, Crawley S, Yang S, et al.
Pancreas
. 2003 Mar;
26(3):e48-54.
PMID: 12657964
Introduction: Ductal adenocarcinoma of the pancreas has recently been suggested to arise from histologically identifiable ductal lesions known as pancreatic intraepithelial neoplasia (PanINs). Altered levels and patterns of mucin gene...