Susanne Aleithe
Overview
Explore the profile of Susanne Aleithe including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
191
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Recent Articles
1.
Mages B, Fuhs T, Aleithe S, Blietz A, Hobusch C, Hartig W, et al.
Mol Neurobiol
. 2021 May;
58(8):4051-4069.
PMID: 33931805
In the setting of ischemic stroke, the neurofilament subunit NF-L and the microtubule-associated protein MAP2 have proven to be exceptionally ischemia-sensitive elements of the neuronal cytoskeleton. Since alterations of the...
2.
Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, et al.
Cell Rep
. 2019 Dec;
29(13):4553-4567.e7.
PMID: 31875560
The Hedgehog (Hh) and Wnt/β-Catenin (Wnt) cascades are morphogen pathways whose pronounced influence on adult liver metabolism has been identified in recent years. How both pathways communicate and control liver...
3.
Mages B, Aleithe S, Blietz A, Krueger M, Hartig W, Michalski D
Neurosci Lett
. 2019 Aug;
711:134405.
PMID: 31374325
Ischemic stroke not only affects neurons, but also glial and vascular elements. The development of novel neuroprotective strategies thus requires an improved pathophysiological understanding of ischemia-affected cell types that comprise...
4.
Aleithe S, Blietz A, Mages B, Hobusch C, Hartig W, Michalski D
Mol Neurobiol
. 2019 May;
56(11):7631-7650.
PMID: 31089963
Experimental stroke studies yielded insights into single reactions of the neurovascular unit (NVU) and associated extracellular matrix (ECM). However, the extent of simultaneous processes caused by ischemia and their underlying...
5.
Marbach-Breitruck E, Matz-Soja M, Abraham U, Schmidt-Heck W, Sales S, Rennert C, et al.
J Hepatol
. 2019 Feb;
70(6):1192-1202.
PMID: 30711403
Background & Aims: The mammalian circadian clock controls various aspects of liver metabolism and integrates nutritional signals. Recently, we described Hedgehog (Hh) signaling as a novel regulator of liver lipid...
6.
Mages B, Aleithe S, Altmann S, Blietz A, Nitzsche B, Barthel H, et al.
Front Cell Neurosci
. 2018 Jul;
12:161.
PMID: 29967576
As part of the neuronal cytoskeleton, neurofilaments are involved in maintaining cellular integrity. In the setting of ischemic stroke, the affection of the neurofilament network is considered to mediate the...
7.
Hartig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, et al.
Front Integr Neurosci
. 2017 Sep;
11:15.
PMID: 28860977
As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic, chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be affected in various neural diseases. Although these...
8.
Michalski D, Pitsch R, Pillai D, Mages B, Aleithe S, Grosche J, et al.
PLoS One
. 2017 Apr;
12(4):e0174996.
PMID: 28445478
Current stroke therapy is focused on recanalizing strategies, but neuroprotective co-treatments are still lacking. Modern concepts of the ischemia-affected neurovascular unit (NVU) and surrounding penumbra emphasize the complexity during the...
9.
Matz-Soja M, Rennert C, Schonefeld K, Aleithe S, Boettger J, Schmidt-Heck W, et al.
Elife
. 2016 May;
5.
PMID: 27185526
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries and is increasing in prevalence. The pathomechanisms, however, are poorly understood. This study assessed the unexpected...
10.
Bottger J, Arnold K, Thiel C, Rennert C, Aleithe S, Hofmann U, et al.
Arch Toxicol
. 2015 Aug;
89(9):1579-88.
PMID: 26233687
Primary hepatocyte cell cultures are widely used for studying hepatic diseases with alterations in hepatic glucose and lipid metabolism, such as diabetes and non-alcoholic fatty liver disease. Therefore, small interfering...