Rolf Gebhardt
Overview
Explore the profile of Rolf Gebhardt including associated specialties, affiliations and a list of published articles.
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Articles
113
Citations
3096
Followers
0
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Recent Articles
1.
Buniatian G, Schwinghammer U, Tremmel R, Cynis H, Weiss T, Weiskirchen R, et al.
Adv Sci (Weinh)
. 2024 Mar;
11(18):e2307734.
PMID: 38430535
The hepatic content of amyloid beta (Aβ) decreases drastically in human and rodent cirrhosis highlighting the importance of understanding the consequences of Aβ deficiency in the liver. This is especially...
2.
Hoehme S, Hammad S, Boettger J, Begher-Tibbe B, Bucur P, Vibert E, et al.
iScience
. 2023 Jan;
26(1):105714.
PMID: 36691615
Partial liver removal is an important therapy option for liver cancer. In most patients within a few weeks, the liver is able to fully regenerate. In some patients, however, regeneration...
3.
Ott F, Korner C, Werner K, Gericke M, Liebscher I, Lobsien D, et al.
Cells
. 2022 May;
11(10).
PMID: 35626717
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of adult organs. Recent data suggest that central metabolic processes and signaling cascades in the liver are controlled...
4.
Busche M, Rabl D, Fischer J, Schmees C, Mayr T, Gebhardt R, et al.
EXCLI J
. 2022 Feb;
21:144-161.
PMID: 35145369
Oxygen plays a fundamental role in cellular energy metabolism, differentiation and cell biology in general. Consequently, oxygen sensing can be used to assess cell vitality and detect specific mechanisms of...
5.
Spormann L, Rennert C, Kolbe E, Ott F, Lossius C, Lehmann R, et al.
Cells
. 2020 Aug;
9(8).
PMID: 32751882
In the liver, energy homeostasis is mainly regulated by mechanistic target of rapamycin (mTOR) signalling, which influences relevant metabolic pathways, including lipid metabolism. However, the Hedgehog (Hh) pathway is one...
6.
Busche M, Tomilova O, Schutte J, Werner S, Beer M, Groll N, et al.
Lab Chip
. 2020 Jul;
20(16):2911-2926.
PMID: 32662810
HepaChip microplate (HepaChip-MP) is a microfluidic platform comprised of 24 independent culture chambers with continuous, unidirectional perfusion. In the HepaChip-MP, an automated dielectrophoresis process selectively assembles viable cells into elongated...
7.
Buniatian G, Weiskirchen R, Weiss T, Schwinghammer U, Fritz M, Seferyan T, et al.
Cells
. 2020 Feb;
9(2).
PMID: 32089540
The function and regulation of amyloid-beta (Aβ) in healthy and diseased liver remains unexplored. Because Aβ reduces the integrity of the blood-brain barrier we have examined its potential role in...
8.
Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, et al.
Cell Rep
. 2019 Dec;
29(13):4553-4567.e7.
PMID: 31875560
The Hedgehog (Hh) and Wnt/β-Catenin (Wnt) cascades are morphogen pathways whose pronounced influence on adult liver metabolism has been identified in recent years. How both pathways communicate and control liver...
9.
Ghallab A, Myllys M, Holland C, Zaza A, Murad W, Hassan R, et al.
Cells
. 2019 Dec;
8(12).
PMID: 31810365
Little is known about how liver fibrosis influences lobular zonation. To address this question, we used three mouse models of liver fibrosis, repeated CCl administration for 2, 6 and 12...
10.
Min Q, Molina L, Li J, Michael A, Russell J, Preziosi M, et al.
Am J Pathol
. 2019 Feb;
189(5):1091-1104.
PMID: 30794807
Hepatoblastoma (HB), the most common pediatric primary liver neoplasm, shows nuclear localization of β-catenin and yes-associated protein 1 (YAP1) in almost 80% of the cases. Co-expression of constitutively active S127A-YAP1...