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Bianca Mages

Explore the profile of Bianca Mages including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 284
Followers 0
Related Specialties
Neurology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Wolfgang Hartig
Dominik Michalski
Martin Krueger
Susanne Aleithe
Stefan Schob
Alexandra Blietz
Henryk Barthel
Bjorn Nitzsche
Constance Hobusch
Karsten Winter
Published In
Brain Struct Funct
Front Cell Neurosci
Mol Neurobiol
Int J Mol Sci
PLoS One
Affiliations
Soon will be listed here.
Recent Articles
1.
Regionally Altered Immunosignals of Surfactant Protein-G, Vascular and Non-Vascular Elements of the Neurovascular Unit after Experimental Focal Cerebral Ischemia in Mice, Rats, and Sheep
Michalski D, Reimann W, Spielvogel E, Mages B, Biedermann B, Barthel H, et al.
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682557
The surfactant protein-G (SP-G) has recently been discovered in the brain and linked to fluid balance regulations. Stroke is characterized by impaired vessel integrity, promoting water influx and edema formation....
2.
SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?
Lohr M, Hartig W, Schulze A, Kroiss M, Sbiera S, Lapa C, et al.
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409086
Targeting molecular alterations as an effective treatment for isocitrate dehydrogenase-wildtype glioblastoma (GBM) patients has not yet been established. Sterol-O-Acyl Transferase 1 (SOAT1), a key enzyme in the conversion of endoplasmic...
3.
Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content
Meinicke A, Hartig W, Winter K, Puchta J, Mages B, Michalski D, et al.
Biomolecules . 2022 Jan; 12(1). PMID: 35053244
The classic surfactant proteins (SPs) A, B, C, and D were discovered in the lungs, where they contribute to host defense and regulate the alveolar surface tension during breathing. Their...
4.
Surfactant protein C is associated with perineuronal nets and shows age-dependent changes of brain content and hippocampal deposits in wildtype and 3xTg mice
Schob S, Puchta J, Winter K, Michalski D, Mages B, Martens H, et al.
J Chem Neuroanat . 2021 Oct; 118:102036. PMID: 34626771
Surfactant protein C (SP-C) modulates cerebrospinal fluid (CSF) rheology. During ageing, its declining levels are accompanied by an increased burden of white matter lesions. Pulmonary SP-C intermediates harbouring the BRICHOS-domain...
5.
Classification of Microglial Morphological Phenotypes Using Machine Learning
Leyh J, Paeschke S, Mages B, Michalski D, Nowicki M, Bechmann I, et al.
Front Cell Neurosci . 2021 Jul; 15:701673. PMID: 34267628
Microglia are the brain's immunocompetent macrophages with a unique feature that allows surveillance of the surrounding microenvironment and subsequent reactions to tissue damage, infection, or homeostatic perturbations. Thereby, microglia's striking...
6.
The Cytoskeletal Elements MAP2 and NF-L Show Substantial Alterations in Different Stroke Models While Elevated Serum Levels Highlight Especially MAP2 as a Sensitive Biomarker in Stroke Patients
Mages B, Fuhs T, Aleithe S, Blietz A, Hobusch C, Hartig W, et al.
Mol Neurobiol . 2021 May; 58(8):4051-4069. PMID: 33931805
In the setting of ischemic stroke, the neurofilament subunit NF-L and the microtubule-associated protein MAP2 have proven to be exceptionally ischemia-sensitive elements of the neuronal cytoskeleton. Since alterations of the...
7.
Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue
Michalski D, Spielvogel E, Puchta J, Reimann W, Barthel H, Nitzsche B, et al.
Front Physiol . 2020 Nov; 11:575598. PMID: 33192578
Ischemic stroke causes cellular alterations in the "neurovascular unit" (NVU) comprising neurons, glia, and the vasculature, and affects the blood-brain barrier (BBB) with adjacent extracellular matrix (ECM). Limited data are...
8.
Spatiotemporal Changes of Cerebral Monocarboxylate Transporter 8 Expression
Wilpert N, Krueger M, Opitz R, Sebinger D, Paisdzior S, Mages B, et al.
Thyroid . 2020 Mar; 30(9):1366-1383. PMID: 32143555
Mutations of monocarboxylate transporter 8 (MCT8), a thyroid hormone (TH)-specific transmembrane transporter, cause a severe neurodevelopmental disorder, the Allan-Herndon-Dudley syndrome. In MCT8 deficiency, TH is not able to reach those...
9.
Simultaneous alterations of oligodendrocyte-specific CNP, astrocyte-specific AQP4 and neuronal NF-L demarcate ischemic tissue after experimental stroke in mice
Mages B, Aleithe S, Blietz A, Krueger M, Hartig W, Michalski D
Neurosci Lett . 2019 Aug; 711:134405. PMID: 31374325
Ischemic stroke not only affects neurons, but also glial and vascular elements. The development of novel neuroprotective strategies thus requires an improved pathophysiological understanding of ischemia-affected cell types that comprise...
10.
Transcriptional Response and Morphological Features of the Neurovascular Unit and Associated Extracellular Matrix After Experimental Stroke in Mice
Aleithe S, Blietz A, Mages B, Hobusch C, Hartig W, Michalski D
Mol Neurobiol . 2019 May; 56(11):7631-7650. PMID: 31089963
Experimental stroke studies yielded insights into single reactions of the neurovascular unit (NVU) and associated extracellular matrix (ECM). However, the extent of simultaneous processes caused by ischemia and their underlying...