Constance Hobusch
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Explore the profile of Constance Hobusch including associated specialties, affiliations and a list of published articles.
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20
Citations
288
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Recent Articles
1.
Neugebauer J, Raulien N, Arndt L, Akkermann D, Hobusch C, Lindhorst A, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684730
Obesity is concurrent with immunological dysregulation, resulting in chronic low-grade inflammation and cellular dysfunction. In pancreatic islets, this loss of function has been correlated with mature β-cells dedifferentiating into a...
2.
Ackermann J, Arndt L, Froba J, Lindhorst A, Glass M, Kirstein M, et al.
Front Immunol
. 2024 Mar;
15:1201439.
PMID: 38482013
Introduction: Obesity is associated with chronic low-grade inflammation of adipose tissue (AT) and an increase of AT macrophages (ATMs) that is linked to the onset of type 2 diabetes. We...
3.
Prehn A, Hobusch C, Hartig W, Michalski D, Krueger M, Flachmeyer B
Front Cell Neurosci
. 2023 Jun;
17:1183232.
PMID: 37342767
In the setting of stroke, ischemia not only impairs neuronal function, but also detrimentally affects the different components of the neurovascular unit, which are shown to be involved in the...
4.
Arndt L, Lindhorst A, Neugebauer J, Hoffmann A, Hobusch C, Alexaki V, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982747
White adipose tissue (WAT) fibrosis, characterized by an excess of extracellular (ECM) matrix components, is strongly associated with WAT inflammation and dysfunction due to obesity. Interleukin (IL)-13 and IL-4 were...
5.
Steinke H, Kurz S, Fischer B, Schuberth S, Hobusch C, Heyde C
J Mech Behav Biomed Mater
. 2022 Aug;
134:105368.
PMID: 35930947
The objective of this study was to evaluate the intrinsic preload of the sacrotuberous ligament. Preload measurements and anatomical experiments were performed on 20 specimens from 10 human cadavers and...
6.
Kulow C, Theopold J, Ehrlich A, Hobusch C, Steinke H
Ann Anat
. 2022 Apr;
243:151938.
PMID: 35367623
Pain over the superior angle of the scapula is a common musculoskeletal symptom. It is often accompanied by radiating pain to the neck, head, and shoulder. The aetiologies can be...
7.
Ackermann J, Arndt L, Kirstein M, Hobusch C, Brinker G, Kloting N, et al.
J Immunol
. 2021 Nov;
207(12):3081-3089.
PMID: 34789558
IL-4 receptor signaling is supposed to play a major role in anti-inflammatory polarization and proliferation of adipose tissue macrophages. In this study, we examined the metabolic and inflammatory phenotype of...
8.
Mages B, Fuhs T, Aleithe S, Blietz A, Hobusch C, Hartig W, et al.
Mol Neurobiol
. 2021 May;
58(8):4051-4069.
PMID: 33931805
In the setting of ischemic stroke, the neurofilament subunit NF-L and the microtubule-associated protein MAP2 have proven to be exceptionally ischemia-sensitive elements of the neuronal cytoskeleton. Since alterations of the...
9.
Brinker G, Froeba J, Arndt L, Braune J, Hobusch C, Lindhorst A, et al.
Eur J Immunol
. 2021 Mar;
51(6):1399-1411.
PMID: 33784418
Obesity is frequently associated with a chronic low-grade inflammation in the adipose tissue (AT) and impaired glucose homeostasis. Adipose tissue macrophages (ATMs) have been shown to accumulate in the inflamed...
10.
Braune J, Lindhorst A, Froba J, Hobusch C, Kovacs P, Bluher M, et al.
Diabetes
. 2020 Nov;
70(2):538-548.
PMID: 33158932
Obesity is associated with chronic low-grade inflammation of visceral adipose tissue (AT) characterized by an increasing number of AT macrophages (ATMs) and linked to type 2 diabetes. AT inflammation is...