Suresh C Jhanwar
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Explore the profile of Suresh C Jhanwar including associated specialties, affiliations and a list of published articles.
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43
Citations
1717
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Recent Articles
1.
Elahi A, Morales C, Xu X, Eliades A, Patsalis P, Abramson D, et al.
Adv Biol Regul
. 2023 Apr;
88:100964.
PMID: 37004354
Small cell lung cancer (SCLC) often exhibits Rb deficiency, TRβ and p130 deletion, and SKP2 amplification, suggesting TRβ inactivation and SKP2 activation. It is reported that SKP2 targeted therapy is...
2.
Tan Y, Sementino E, Cheung M, Peri S, Menges C, Kukuyan A, et al.
Clin Cancer Res
. 2020 Nov;
27(4):1200-1213.
PMID: 33203643
Purpose: Receptor-interacting protein kinase 3 (RIPK3) phosphorylates effector molecule MLKL to trigger necroptosis. Although RIPK3 loss is seen in several human cancers, its role in malignant mesothelioma is unknown. This...
3.
Jhanwar S, Xu X, Elahi A, Abramson D
Adv Biol Regul
. 2020 Sep;
78:100723.
PMID: 32992231
Cancer as a genetic disease is by now well recognized. Genomic analysis of cancer cells, therefore, has greatly enhanced our ability to identify genetic alterations associated with various cancer types,...
4.
Granitto S, Kolachana P, Antonescu C, Johnson R, DeMatteo R, Jhanwar S
Cancer Genomics Proteomics
. 2019 Aug;
1(2):105-116.
PMID: 31394675
Gastrointestinal stromal tumor (GIST) is the most commonly occurring mesenchymal neoplasm of the gastrointestinal tract, accounting for 80 percent of these tumors. GIST is highly unresponsive to standard chemotherapy, particularly...
5.
Xu X, Li Z, Liu A, Fan X, Hu D, Qi D, et al.
Cancer Res
. 2017 Oct;
77(24):6838-6850.
PMID: 28972075
Germline mutations strongly predispose humans to cone precursor-derived retinoblastomas and strongly predispose mice to pituitary tumors, yet shared cell type-specific circuitry that sensitizes these different cell types to the loss...
6.
Pappas L, Xu X, Abramson D, Jhanwar S
Adv Biol Regul
. 2017 Mar;
64:20-32.
PMID: 28242412
Genomic instability (GIN) is a hallmark of most cancer cells. However, compared to most human cancer cell types, the retinoblastoma tumor cells show a relatively stable genome. The fundamental basis...
7.
Shah G, Landau H, Londono D, Devlin S, Kosuri S, Lesokhin A, et al.
Leuk Lymphoma
. 2017 Jan;
58(8):1823-1831.
PMID: 28078910
We aimed to identify whether the use of autologous hematopoietic cell transplantation (HCT) impacts outcomes for multiple myeloma patients with gains of chromosome 1q (+1q). We retrospectively identified 95 patients,...
8.
Garcia-Rendueles M, Ricarte-Filho J, Untch B, Landa I, Knauf J, Voza F, et al.
Cancer Discov
. 2015 Sep;
5(11):1178-93.
PMID: 26359368
Unlabelled: Ch22q LOH is preferentially associated with RAS mutations in papillary and in poorly differentiated thyroid cancer (PDTC). The 22q tumor suppressor NF2, encoding merlin, is implicated in this interaction...
9.
Jhanwar S
Adv Biol Regul
. 2014 Dec;
58:28-37.
PMID: 25499150
Myelodysplastic syndromes (MDS) are a highly heterogenous group of hematopoietic tumors, mainly due to variable clinical features and diverse set of cytogenetic, molecular genetic and epigenetic lesions. The major clinical...
10.
Xu X, Singh H, Wang L, Qi D, Poulos B, Abramson D, et al.
Nature
. 2014 Sep;
514(7522):385-8.
PMID: 25252974
Retinoblastoma is a childhood retinal tumour that initiates in response to biallelic RB1 inactivation and loss of functional retinoblastoma (Rb) protein. Although Rb has diverse tumour-suppressor functions and is inactivated...