Sunil K Pandey
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Explore the profile of Sunil K Pandey including associated specialties, affiliations and a list of published articles.
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13
Citations
194
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Recent Articles
1.
Hansen A, Christensen H, Pandey S, Sergeev E, Valentini A, Dunlop J, et al.
ChemMedChem
. 2021 Jul;
16(21):3326-3341.
PMID: 34288488
Free fatty acid receptor 2 (FFA2) is a sensor for short-chain fatty acids that has been identified as an interesting potential drug target for treatment of metabolic and inflammatory diseases....
2.
Ndukwe I, Lam Y, Pandey S, Haug B, Bayer A, Sherer E, et al.
Chem Sci
. 2021 Jun;
11(44):12081-12088.
PMID: 34094423
Structural features of proton-deficient heteroaromatic natural products, such as the breitfussins, can severely complicate their characterization by NMR spectroscopy. For the breitfussins in particular, the constitution of the five-membered oxazole...
3.
Guttormsen Y, Fairhurst M, Pandey S, Isaksson J, Haug B, Bayer A
Molecules
. 2020 Oct;
25(20).
PMID: 33096668
Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of...
4.
Hansen K, Andersen J, Bayer A, Pandey S, Lorentzen M, Jorgensen K, et al.
J Med Chem
. 2019 Oct;
62(22):10167-10181.
PMID: 31647655
In this work, we demonstrate that the indole-oxazole-pyrrole framework of the breitfussin family of natural products is a promising scaffold for kinase inhibition. Six new halogenated natural products, breitfussin C-H...
5.
Hegvik T, Waloen K, Pandey S, Faraone S, Haavik J, Zayats T
Mol Psychiatry
. 2019 Oct;
26(8):4004-4015.
PMID: 31628418
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder with only symptomatic care available. Genome-wide association (GWA) studies can provide a starting point in the search for novel drug targets and...
6.
Hansen A, Sergeev E, Pandey S, Hudson B, Christiansen E, Milligan G, et al.
J Med Chem
. 2017 Jun;
60(13):5638-5645.
PMID: 28570808
The free fatty acid receptor 2 (FFA2/GPR43) is considered a potential target for treatment of metabolic and inflammatory diseases. Here we describe the development of the first fluorescent tracer for...
7.
Bjorkman L, Martensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, et al.
Mol Cell Biol
. 2016 Aug;
36(20):2583-95.
PMID: 27503855
Ligands with improved potency and selectivity for free fatty acid receptor 2 (FFA2R) have become available, and we here characterize the neutrophil responses induced by one such agonist (Cmp1) and...
8.
Due-Hansen M, Pandey S, Christiansen E, Andersen R, Hansen S, Ulven T
Org Biomol Chem
. 2015 Nov;
14(2):430-433.
PMID: 26586516
A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of...
9.
Sergeev E, Hansen A, Pandey S, MacKenzie A, Hudson B, Ulven T, et al.
J Biol Chem
. 2015 Nov;
291(1):303-17.
PMID: 26518871
Short chain fatty acids (SCFAs) are produced in the gut by bacterial fermentation of poorly digested carbohydrates. A key mediator of their actions is the G protein-coupled free fatty acid...
10.
Hudson B, Due-Hansen M, Christiansen E, Hansen A, MacKenzie A, Murdoch H, et al.
J Biol Chem
. 2013 Apr;
288(24):17296-312.
PMID: 23589301
FFA2 is a G protein-coupled receptor that responds to short chain fatty acids and has generated interest as a therapeutic target for metabolic and inflammatory conditions. However, definition of its...